fa بررسی اثر برخی موتاسیون ژنی در بیماری اندومتریوز با روش‌های داده کاوی کارآزمایی بالینی Clinical Trials <p><strong><em>Background and Objective:</em></strong> Endometriosis is a prevalent disease in women which may lead to infertility or low fertility. Grasping the genetic grounds for the disease may contribute to its treatment because it is presumed that genetic factors predispose to endometriosis risk factors.&nbsp;</p> <p><strong><em>Materials and Methods:</em></strong> 9 genes involved in endometriosis in patients suffering from endometriosis and also in healthy individuals (total 260 samples) were examined. The data were obtained from Ibn Sina (Jahad Daneshgahi) Research Center of new Technologies in Biological Sciences Institute. The study incorporated standard process Crisp for data mining. Weka data mining and software modeling were implemented with the aid of four algorithms.</p> <p><strong><em>Results:</em></strong> Comparison of four algorithms implied prominent accuracy of K-Star model. Meanwhile, filtering, while reducing the percentage of models, presented a positive impact on the MLP model. The lowest percentage pertained to Na&iuml;ve Bayes.</p> <p><strong><em>Conclusion:</em></strong> K-Star model without any filtering proved to have the highest accuracy in the early diagnosis of endometriosis.</p> <p></p><p></p><p align="center" dir="RTL"></p> Keywords: Data Mining, Endometriosis, Classification, Weka, MLP, K-star, Naïve bayes, J48 97 106 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-956&slc_lang=fa&sid=1 Leyla Bahrami لیلا بهرامی 5200319475328460053513 5200319475328460053513 No Dept. of Computer, Islamic Azad University, Zanjan Branch, Zanjan, Iran دانشگاه آزاد زنجان Bahram Sadeghi Bigham بهرام صادقی بی غم b_sadeghi_b@iasbs.ac.ir 5200319475328460053514 5200319475328460053514 Yes Dept. of Computer, Faculty of Computer, University of Basic Sciences, Zanjan, Iran تحصیلات تکمیلی زنجان Kurosh Kamali کوروش کمالی 5200319475328460053515 5200319475328460053515 No Dept. of Epidemiology, Metabolic Disease Research Center, Zanjan University of Medical Sciences, Zanjan, Iran دانشگاه علوم پزشکی زنجان