Journal of Advances in Medical and Biomedical Research

en Prevalence of Bacterial Isolates Related to the Meningitis and Bacteremia in two Hospitals During 2016-2017 Medical Biology Medical Biology مقاله پژوهشی Original Research Article Background and Objective: Hospitals niche as a source and repository for microbial infections are playing a significant role in the health of hospitalized patients. Bacteria are playing an essential role in human and animal blood infections and meningitis. The prevalence of bacterial agents and their susceptibility patterns are fundamental goals of current research. Materials and Methods: Sampling was carried out in two main educational hospitals, Sari City, Iran, from April 2016 to March 2017. After traditional biochemical tests, susceptibility testing of isolates was performed taking advantage of Kerby-Bauer. Subsequently, the frequency of related bacterial agents to meningitis and bacteremia and their susceptibility patterns were analyzed. Results: Frequencies of bacterial isolates in Bouali and Imam Hospitals for meningitis (1.9%, 3.5%), bacteremia (31.9%, 26.3%), and urinary tract infection (UTI) were screened (66.2%, 70.1%). Staphylococcus aureus (41.7%) and Streptococcus pneumoniae (45%) were the highest isolates of meningitis in the mentioned hospital. These values to bacteremia were as follows: Gram-negative Staphylococci (30.7%), Escherichia coli (30%). Coagulase- negative Staphylococci isolates recovered from meningitis were completely sensitive to ciprofloxacin and Gentamycin. In addition, P. aeruginosa, Klebsiella and Acinetobacter spp showed higher than 90% resistance against ampicillin. E. coli, Klebsiella spp and S. aureus showed 100% resistance to amoxiclav; while Klebsiella spp were completely sensitive to amoxiclav. Conclusion: Given the bacterial isolates detected from hospital wards and following the findings prompt diagnosis method is essential to control infections and the proper use of effective antibiotics. Antibiotic resistance pattern, Meningitis, Bacteremia, Hospital-acquired infections 162 169 http://journal.zums.ac.ir/browse.php?a_code=A-10-5288-3&slc_lang=en&sid=1 Bahman Mirzaei dr.bahman.m@gmail.com 5200319475328460073420 5200319475328460073420 Yes Dept. of Medical Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Ryhaneh Babaei rey.babaei@gmail.com 5200319475328460073421 5200319475328460073421 No Dept. of Medical Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Maryam Jalali Jalaimaryam@yahoo.com 5200319475328460073422 5200319475328460073422 No Dept. of Medical Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Hamid Reza Goli drbahman@zums.ac.ir 5200319475328460073423 5200319475328460073423 No Dept. of Medical Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Mohammad Reza Haghshenas haghshenas201@yahoo.com 5200319475328460073424 5200319475328460073424 No Dept. of Medical Microbiology and Virology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Negin Hosseini hosseini@gmail.com 5200319475328460073425 5200319475328460073425 No Dept. of Medical Microbiology and Virology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Ebrahim Shafaie e.shafaei@yahoo.com 5200319475328460073426 5200319475328460073426 No Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran