Journal of Advances in Medical and Biomedical Research

en Phenotype evaluation in patients with obstructive sleep apnea (AHI>15) Clinical Medicine Clinical Medicine مقاله پژوهشی Original Research Article Background and Objectives: Obstructive sleep apnea is the most common sleep-related breathing disorders characterized by repeated obstruction of the upper airways (pharynx) during sleep, which can lead to or arousal and decreased arterial oxygen saturation. This study compares apnea index < 5 with apnea index >5 in patients suffering from obstructive sleep apnea with AHI> 15. Materials and Methods: This cross-sectional study was performed on patients with obstructive sleep apnea (OSA) in Imam Khomeini Hospital sleep lab in Tehran, Iran between 2023 and 2024. Demographic information (patient name, age, sex, menopausal status, history of smoking and psychotropic substances, history of alcohol consumption, BMI, neck circumference, and patient's blood pressure status) were recorded. Also, excessive drowsiness status using Epworth Scale questionnaire, Snoring status during sleep, ODI Saturation test, apnea index and apnea-hypopnea index, and oxygen saturation <90% during sleep was recorded. Furthermore, the type of treatment prescribed (medication, surgery, CPAP or Bilevel positive airway pressure [BiPAP]), compliance with the prescribed treatment and the number of hours (at night) and months of use of the instrument were recorded. The collected data were analyzed using SPSS statistical software version 22. A p-value less than 0.05 was statistically significant. Results: Study population consisted of 59 females (52.7%) and 53 males (47.3%). The mean age of patients was 51±13.4 years. Furthermore,111 patients (99.1%) had no history of smoking and use of psychedelics. 32.1% of had a history of HTN. Mean BMI was 31.84 ± 7.55, mean neck circumference was 40.83. BMI and neck circumference of women were lower than men. The average ODI was 36.1, which was higher in women than men. The mean EP worth Scale was 11.98±5, the mean AHI of patients was 43.14 ± 31.96. Of the 28 patients who provided the device, 15 had apnea less than 5 and 13 had apnea > 5. Of the 15 people with apnea less than 5, all used the instrument for more than 4 hours, and 14 continued its use after 30 months. Of the 13 people with apnea above 5, 12 were still using it for more than 4 hours and 11 after 3 months. Conclusion: Our finding indicated that solving the problems and inability of instrument provision can be effective in increasing treatment compliance. Although a significant number of patients did not obtain the instrument, of those who did, the combination of 4 hours a day and more than 3 hours was appropriate.   Phenotype, Obstructive sleep apnea, Apnea Hypopnea Index. 23 23 http://journal.zums.ac.ir/browse.php?a_code=A-10-1250-3&slc_lang=en&sid=1 Nooshin jalili dr.nooshinjalili@zums.ac.ir 5200319475328460089013 5200319475328460089013 Yes Department of Internal Medicine, School of Medicine Vali-e-Asr Hospital hamidreza abtahi hamidr.rezaabtahi@tums.ac.ir 5200319475328460089014 5200319475328460089014 No advanced thoracic research,tehran university of medical science Besharat Rahimi Besharatrahimi@yahoo.com 5200319475328460089015 5200319475328460089015 No advanced thoracic research,tehran university of medical science