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1- Universitas Diponegoro
2- Dr. Kariadi Hospital
3- Universitas Diponegoro ,dwiretno@fk.undip.ac.id
2- Dr. Kariadi Hospital
3- Universitas Diponegoro ,
Abstract: (59 Views)
Background: Sepsis is a condition with various body responses and often results in death from infectious diseases. Serum lactate levels, elevated during hypoxia, stress, and critical illness, can serve as a sensitive yet non-specific indicator of metabolic stress. Hypoalbuminemia may be present in sepsis and exacerbate its severity. Researchers propose the lactate/albumin ratio (LAR) as a marker associated with multi-organ failure, and the SOFA score assesses mortality in critically ill patients.
Objective: To prove the correlation between lactate, albumin, LAR, and the SOFA score in septic patients.
Methods: This study included 35 sepsis patients. Lactate and albumin levels were obtained from the electronic medical record; the LAR assessment and SOFA score were calculated manually. Data analysis was carried out using the Spearman test with a significance level of p < 0.05.
Results: The median levels of lactate, albumin, and LAR were 5.50 (1.90–10.40) mmol/L, 2.40 (0.90–3.70) g/dL, and 2.29 (0.53–7.46), respectively. The results of the Spearman correlation test between albumin levels and the SOFA score showed no correlation (p = 0.643 and r = -0.081). The correlation test between lactate, LAR, and the SOFA score showed a significant correlation (p = 0.002 and r = 0.498, p = 0.001 and r = 0.538).
Conclusion: There is a moderate positive correlation between lactate, LAR, and the SOFA score, there is no correlation between albumin levels and the SOFA score.
Objective: To prove the correlation between lactate, albumin, LAR, and the SOFA score in septic patients.
Methods: This study included 35 sepsis patients. Lactate and albumin levels were obtained from the electronic medical record; the LAR assessment and SOFA score were calculated manually. Data analysis was carried out using the Spearman test with a significance level of p < 0.05.
Results: The median levels of lactate, albumin, and LAR were 5.50 (1.90–10.40) mmol/L, 2.40 (0.90–3.70) g/dL, and 2.29 (0.53–7.46), respectively. The results of the Spearman correlation test between albumin levels and the SOFA score showed no correlation (p = 0.643 and r = -0.081). The correlation test between lactate, LAR, and the SOFA score showed a significant correlation (p = 0.002 and r = 0.498, p = 0.001 and r = 0.538).
Conclusion: There is a moderate positive correlation between lactate, LAR, and the SOFA score, there is no correlation between albumin levels and the SOFA score.
Type of Study: Original Research Article |
Subject:
Clinical Medicine
Received: 2025/03/16 | Accepted: 2025/07/26 | Published: 2025/08/8
Received: 2025/03/16 | Accepted: 2025/07/26 | Published: 2025/08/8
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