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1- Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
2- Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. ,shalalehaghaei@gmail.com
3- Department of Orthopedic Surgery, Shohada Educational Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
2- Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. ,
3- Department of Orthopedic Surgery, Shohada Educational Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract: (102 Views)
This case report describes a 53-year-old female with newly diagnosed B-cell acute lymphoblastic leukemia (ALL) who developed septic arthritis due to Klebsiella pneumoniae during induction chemotherapy with a modified CALGB protocol. The diagnosis was challenging, requiring multiple imaging modalities (ultrasound, MRI, and PET scan) and ultimately confirmed via synovial fluid culture obtained through arthrotomy. Despite targeted antibiotic therapy and surgical intervention, the patient experienced persistent joint dysfunction, necessitating referral for total hip arthroplasty. This case highlights the importance of high clinical suspicion for septic arthritis in immunocompromised patients, the critical role of synovial fluid analysis in diagnosis, and the need for multidisciplinary management.
Type of Study: Case Report Article |
Subject:
Clinical Medicine
Received: 2025/04/3 | Accepted: 2025/07/26 | Published: 2025/08/8
Received: 2025/04/3 | Accepted: 2025/07/26 | Published: 2025/08/8
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