fa بررسی تنوع ژنوتیپی سویه‌های بالینی سالمونلا انتریکا سروتایپ اینفنتیس به روش ریبوتایپینگ کارآزمایی بالینی Clinical Trials <p>Background and Objective: Salmonella spp. are enteric pathogens with a worldwide distribution comprising a large number of serovars characterized by different hosts and distribution. Among Salmonella spp., the number of infections and diseases caused by the serotype Salmonella enterica serovar Infantis started to increase significantly in the last decade. The aim of this study was to investigate the genetic diversity of the clinical stains of Salmonella enterica serovar Infantis isolated in Tehran, Iran by using the Ribotyping method. Materials and Methods: In this descriptive study from November 2007 to December 2010, clinical samples, collected from different hospitals in Tehran, were investigated for detection of Salmonella enterica serovar Infantis. Bacterial isolation and identification was achieved through biochemical and bacteriological methods. The Ribotyping technique was applied for the molecular typing of the strain of Salmonella enterica serovar Infantis. Results: Out of the 26 Salmonella serogroup C samples isolated in this study, 19 strains (73%) belonged to Salmonella enterica serotype Infantis. Ribotyping results divided Salmonella enterica serovar Infantis stains into 9 clusters (1c to 9c). The majority (7) of the strains belonged to cluster 1c. Conclusion: The results obtained from the Ribotyping patterns indicate that Salmonella enterica serovar Infantis strains, circulating among the patients in Tehran, belong to a diverse number of clones. Moreover, our data show that Ribotyping is an appropriate method for the molecular typing of Salmonella enterica serovar Infantis strains.</p> Keywords: Gastroenteritis, Salmonella enterica serovar infantis, Ribotyping 75 84 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-656&slc_lang=fa&sid=1 Reza Ranjbar رضا رنجبر ranjbar@bmsu.ac.ir 5200319475328460059821 5200319475328460059821 Yes Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IR Iran. Meysam Sarshar میثم سرشار 5200319475328460059822 5200319475328460059822 No Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IR Iran. Nour Khoda Sadeghifard نور خدا صادقی فرد 5200319475328460059823 5200319475328460059823 No Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, IR Iran