fa ارتباط بین تهوع و استفراغ شدید حاملگی با سرولوژی مثبت هلیکوباکتر پیلوری <p style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><strong><em>Background and Objective:</em></strong> HG is a severe form of expectancy nausea and vomiting, occurring in 0/5 to 2% of the expectancies. The etiology of HG is unknown, though hormonal stimuli, and psychologic predisposition are attributable to the condition. Recent studies suggest a relationship between HG and H.pylori infection. The aim of this study was to investigate the&nbsp; relationship between HG and H.pylori infection.<br> <strong><em>Material and Methods:</em></strong> Forty pregnant women with HG (Treatment group) and forty asymptomatic pregnant women (control group) were assigned into the research from April &nbsp;to August 2006. Specific serum immunoglobulin G (IgG) for H.pylori was assayed by ELISA. The data was analyzed using SPSS software, Chi-Square and T-test.<br> <strong><em>Results:</em></strong> Out of 40 pregnant women with HG 25 individuals (62/5%) were found to have serologically positive H.pylori, whereas in asymptomatic pregnant women 19 (47.5%) individuals were positive, which shows no significant difference between H.Pylori infection with HG (P=0.178). No significant difference was observed between positive H.pylori and the number of pregnancy, body mass index (BMI), and duration of &nbsp;hospital stay.<br> <strong><em>Conclusion:</em></strong> Since HG has a multifactorial etiology and with regard to high prevalenve of H pylori in our country, research studies with higher sample sizes and utilization of more sensitive diagnostic methods for the detection of active H pylori is recommended.</span></span></p> Hyperemesis gravidrum, Helicobacter pylori, Zanjan 27 34 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-74&slc_lang=fa&sid=1 Haleh Rahmanpour هاله رحمانپور haleh509@zums.ac.ir 5200319475328460057918 5200319475328460057918 Yes Vali-e-Asr Hospital, Metabolic Diseases Research Center, Zanjan University of Medical Sciences, Zanjan, Iran Seyed Nejat Hosseini سید نجات حسینی 5200319475328460057919 5200319475328460057919 No Seyed Nouraldin mousavinasab سید نورالدین موسوی نسب 5200319475328460057920 5200319475328460057920 No Morteza Nazarian مرتضی نظریان 5200319475328460057921 5200319475328460057921 No Maryam Khodayar مریم خدایار 5200319475328460057922 5200319475328460057922 No