fa مقاومت آنتی‌بیوتیکی میکروب‌های بیماری‌زای شایع در کشت ادرار بیماران در بخش‌های اطفال، نوزادان، زنان و اعصاب مرکز‌ آموزشی، درمانی ولی‌عصر(عج) زنجان مقاله پژوهشی Original Research Article <p style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><strong><em>Background and Objective</em></strong><em>:</em> Extensive use of antibiotics in medicine has led to resistance of microorganisms in urinary tract infection (UTI) in both children and adults. Therefore, conducting studies on antibiotic susceptibility is needed for selection of antibiotics based on regional studies.<br> <strong><em>Materials and Methods:</em></strong> During the year 2006 urine samples from all symptomatic patients admitted to neonatal, pediatrics, obstetric and neurologic wards were collected through midstream clean-catch, catheterization, or urine bags. An antibiogram test was performed for all 118 urine samples which were culture positive.<br> <strong><em>Results:</em></strong> The most common organisms found in neonatal urine culture were <em>klebsiella pneumonia</em> (44/5%) followed by <em>Escherichia coli</em> (33/5%). <em>Escherichia coli</em> was the most common organism in pediatrics (41%), obstetric (46%), and neurologic wards (73%). Resistance to ampicillin (82/6%) and cefixim (73/6%) was significant in all samples. Ciprofloxacine was the most effective drug against <em>E.coli</em> and <em>klebsiella pneumonia </em>in all wards (resistance rate: 24/1%) followed by nitrofurantion (resistance rate: 41/4%), ceftriaxone (resistance rate: 44/8%) and amikacin (resistance rate: 51/9%). Vancomycine was the most effective drug against <em>staphylococcus epidermidis </em>(resistance rate: 37/1%) followed by cephtasidim (resistance rate: 40/1%) and ciprofloxacine (resistance rate: 48/5%).<br> <strong><em>Conclusion:</em></strong> Unfortunately due to irrational use of antibiotics, high resistance to ampicillin, cefixim, gentamycin, cotrimoxazol, and some other drugs was observed. Continuous studies regarding the drug resistance are recommended for better assessment in the future.</span></span></p> Drug resistance, Antibiogram, Antibiotic, Urinary traet infection 79 88 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-812&slc_lang=fa&sid=1 Seyedeh Zohreh Torabi سیده زهره ترابی drztorabi@yahoo.com 5200319475328460057981 5200319475328460057981 Yes Department of Pediatrics, Vali-e- Asr Hospital, Zanjan University of Medical Sciences, Zanjan, Iran Behnaz Falak-ul-Aflaki بهناز فلک‌الافلاکی 5200319475328460057982 5200319475328460057982 No Farzaneh Moezzi فرزانه معزی 5200319475328460057983 5200319475328460057983 No