fa مقایسه‌ی اثر تزریق تریامسینولون استوناید در داخل زجاجیه و زیر کپسول تنون بر میزان دید بیماران مبتلا به دیابتیک رتینوپاتی کارآزمایی بالینی Clinical Trials <p><strong><em>Background and Objective</em></strong><strong>:</strong> Macular edema is an important cause of visual loss in diabetic patients which can lead to permanent vision loss in untreated cases. This study compares the efficacy of intravitreal injection and the sub-tenon capsule of triamcinolone on the visual acuity in patients with diabetic retinopathy.</p> <p><strong><em>Materials and methods</em></strong><strong>:</strong> In this randomized clinical trial study, 82 diabetic retinopathy eyes were randomly assigned to intravitreal triamcinolone injection group and 74 eyes to sub tenon capsule injection. In terms of visual acuity and intraocular pressure, patients were followed up after first week, first month, and 3^rd month. The collected data were analyzed using ANOVA with repeated data (Repeated ANOVA) and&nbsp; Stata software (version 13).</p> <p><strong><em>Results</em></strong><strong>:</strong> Crude comparison between groups&nbsp; did not exhibit significant differences. However, by controlling the confounding baseline effect, level of visual acuity, <a>logMar</a><span dir="RTL"><a href="#_msocom_1" id="_anchor_1" name="_msoanchor_1">[d1]</a>&nbsp;</span> of the visual acuity in the&nbsp; intravitreal injection group (-0.78) was significantly less than the sub-tenon capsule group (-0.67). Also, after controlling for other confounding variables (age and sex), the mean IOP was significantly higher in the intravitreal injection group.</p> <p><a><strong><em>Conclusion</em></strong></a><strong>:</strong> <span dir="RTL"><a href="#_msocom_2" id="_anchor_2" name="_msoanchor_2">[d2]</a>&nbsp;</span>Visual acuity in intravitreal injection group was significantly less than the sub-tenon capsule group and also the mean IOP was higher in the intravitreal injection group. Therefore, sub-tenon capsule of triamcinolone stands out as a superior approach.</p> <p></p><p></p> <div><div id="_com_1"></div></div> <p></p> Keywords: Triamcinolone, Macular edema, Diabetic retinopathy 1 9 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-922&slc_lang=fa&sid=1 Reza Rezaei رضا رضایی dr.rezarezaei@arakmu.ac.ir 5200319475328460053814 5200319475328460053814 Yes Dept. of Ophtalmology, Arak University of Medical Sciences, Arak, Iran دانشگاه علوم پزشکی اراک Amir Almasi-Hashiani امیر الماسی حشیانی 5200319475328460053815 5200319475328460053815 No Dept. of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran مرکز تحقیقات اپیدمیولوژی باروری تهران Abdollah Rashidi عبدالله رشیدی 5200319475328460053816 5200319475328460053816 No Dept. of Ophtalmology, Arak University of Medical Sciences, Arak, Iran دانشگاه علوم پزشکی اراک Seyed Morteza Vaez سیدمرتضی واعظ 5200319475328460053817 5200319475328460053817 No Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran دانشگاه علوم پزشکی شاهرود Ahmad Khosravi احمد خسروی 5200319475328460053818 5200319475328460053818 No Center for Health-Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran دانشگاه علوم پزشکی شاهرود