fa تاثیر لیزر گالیوم-آرسناید (904 نانومتر) بر کاهش سطح زخم و تغییر ایندکس مچ پایی-بازویی در زخم پای دیابتیک کارآزمایی بالینی Clinical Trials <p><strong><em>Background and Objective</em></strong>: Diabetic foot ulcer as one of the most common complications of diabetes mellitus is known to be resistant to conventional treatment of wound healing. The objective of this study was to evaluate the efficacy of low level laser therapy with Ga-As laser, 904 nm, in foot ulcer healing of type 2diabetic patients.</p> <p><strong><em>Materials and Methods: </em></strong>27 patients with Type 2 diabetes mellitus suffering from Wagner Grade II ischemic foot ulcers were randomly divided into two groups: Ga-As laser (n=15) and placebo (n=12). In the laser therapy group, Ga-As, (2 j/cm², 90mW) was applied while in the placebo group laser probe was set similar to the laser group,&nbsp; but the power was off. Conventional treatment after laser therapy was done for both groups in a similar vein, i.e., three times a week for twelve sessions. Wound surface area and temperature around the wound (before and after therapy) in the 1^st, 6^th and 12^th sessions and Ankle Brachial Index (ABI) in the1^st and 12^th sessions were recorded.</p> <p><strong><em>Results</em></strong><strong><em>:</em></strong> Throughout the 6^th and 12^th sessions, reduction in wound surface percentatage in comparison with baseline was significantly (P<0.05) higher in the laser group (43.98&plusmn;6.36, 72.08&plusmn;7.22 respectively) than the placebo group (6.48&plusmn;7.98, 12.69&plusmn;9.05 respectively), but the skin temperature and ABI values did not show any significant difference.</p> <p><strong><em>Conclusion:</em></strong> Ga-As laser using photochemical and non-thermal mechanisms may be effective on the acceleration of diabetic chronic foot ulcer closure.</p> <p></p> Keywords: Gallium-Arsenide Laser, Diabetic foot ulcer, Wound closure, Ankle brachial index 20 21 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-924&slc_lang=fa&sid=1 Mahsa Hoseini Sanati مهسا حسینی صنعتی 5200319475328460053825 5200319475328460053825 No Dept. of Physical Therapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. دانشگاه تربیت مدرس تهران Giti Torkaman گیتی ترکمان torkamg@modares.ac.ir 5200319475328460053826 5200319475328460053826 Yes Dept. of Physical Therapy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. دانشگاه تربیت مدرس تهران Mahdi Hedayati مهدی هدایتی 5200319475328460053827 5200319475328460053827 No Cellular and Molecular Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. دانشگاه علوم پزشکی شهید بهشتی Manuchehr Iranparvar Alamdari منوچهر ایرانپرور علمداری 5200319475328460053828 5200319475328460053828 No Dept .of Endocrinology, Faculty Medicine, Ardabil University of Medical Sciences, Ardabil, Iran. دانشگاه علوم پزشکی اردبیل