fa مقایسه‌ی اثر ونتولین و سالین هیپرتونیک 3 درصد در سیر بهبودی برونشیولیت حاد در کودکان زیر 2 سال در بیمارستان هاجر شهرکرد کارآزمایی بالینی Clinical Trials <p><strong><em>Background and Objective:</em></strong> Acute bronchiolitis is one of the most common reasons for inflammation, small airways obstruction, and lower respiratory tract infection in infancy. Owing that there has been no study on the efficacy of hypersaline 3% in the treatment of acute bronchiolitis in Iran, the present study was undertaken to deal with this issue.</p> <p><strong><em>Materials and Methods: </em></strong>This double-blinded clinical trial was carried out in Hajar Hospital of Shahrekord in 2013-2014. 70 patients under 2 years of age with bronchiolitis were assigned to two groups of 35 each. The first group received nebulized Ventolin while the second group was given nebulized hypersaline 3% three times a day. Subsequent to these administrations, recovery duration was compared in both groups.</p> <p><strong><em>Results:</em></strong> The mean and standard deviation of recovery duration in the Ventolin group was 4.14&plusmn;0.9 days and in the hypersaline 3% group was 3.06&plusmn;0.6 days. T-test and mean recovery duration was significantly lower in the hypersaline 3% group (P<0.001).</p> <p><strong><em>Conclusion:</em></strong> Nebulizer hypersaline 3% had a better therapeutic effect than Ventolin in the treatment of acute bronchiolitis. Therefore, the use of this drug, rather than Ventolin, is recommended for the treatment of acute bronchiolitis in children under two years of age.</p> <p></p><p></p> Keywords: Bronchiolitis, Ventolin, Hypertonic Saline solution 1 9 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-935&slc_lang=fa&sid=1 Mohammad Ali Zamani محمدعلی زمانی 5200319475328460053662 5200319475328460053662 No Dept. of Pediatrics, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran. دانشگاه علوم پزشکی شهرکرد Mohammad Kazem Nourbakhsh سیدمحمدکاظم نوربخش 5200319475328460053663 5200319475328460053663 No Dept.of Pediatrics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. دانشگاه علوم پزشکی تهران Mahmood Rafieian محمود رفیعیان 5200319475328460053664 5200319475328460053664 No Herbal Medicine Research Center, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran. دانشگاه علوم پزشکی شهرکرد Zahra Keyvani Hafshejani زهرا کیوانی هفشجانی keivaniz@yahoo.com 5200319475328460053665 5200319475328460053665 Yes Dept. of Nursing, Shahrekord University of Medical Sciences, Shahrekord, Iran. دانشگاه علوم پزشکی شهرکرد Saeed Heidari Soureshjani سعید حیدری سورشجانی 5200319475328460053666 5200319475328460053666 No Dept. of Research and Technology, Shahrekord University of Medical Sciences, Shahrekord, Iran. دانشگاه علوم پزشکی شهرکرد