fa تاثیر 12 هفته تمرین هوازی با شدت متوسط بر سطوح IL-6، IL-10 و حافظه‌ی میان مدت زنان 50 تا 65 ساله مبتلا به سندروم متابولیک کارآزمایی بالینی Clinical Trials <p><strong><em>Backgrounds and Objective:</em></strong> The main important factors in decreasing cognitive performance are aging, proinflammatory and metabolic syndrome. The aim of this research was investigation the effect of twelve week aerobic exercise whit moderate intensity on IL-6, IL-10, and cognitive performance in 50-65 years old women with syndrome metabolic.</p> <p><strong><em>Materials and Methods:</em></strong> 24 women with metabolic syndrome (MetS) voluntarily took part in the study and were divided into two groups: MetS exercise (ME), MetS control (MC). The ME group participated in an aerobic exercise training (AT) program (12 weeks), three sessions per week, each session containing three performance parts and two rest parts. Also blood samples were drawn before and after training to evaluate levels of IL-6, IL-10. Cognitive performance was measured by digit span memory test. Data were analyzed using Pearson coefficient, pried-sample T-Test, and independent samples T-Test.</p> <p><strong><em>Results: </em></strong>After three months of aerobic exercise, IL-6 levels decrease while IL-10 levels and cognitive performance increased significantly (P<0.05). IL-6, IL-10, and cognitive performance in the control group were not altered after three months (P<0.05).</p> <p><strong><em>Conclusion:</em></strong> These findings indicate that three months of aerobic exercise can increase IL-10 level and decrease IL-6 while ameliorating cognitive performance.</p> <p></p><p></p> Keywords: Aerobic exercise, IL-6, IL10, Cognitive performance, Metabolic syndrome 1 12 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-1007&slc_lang=fa&sid=1 Ali Osali علی اوصالی 5200319475328460053300 5200319475328460053300 Yes Dept. of Exercise Physiology, Faculty of Exercise, Tehran University, Tehran, Iran دانشگاه تهران Sirous Choobineh سیروس چوبینه 5200319475328460053301 5200319475328460053301 No Dept. of Exercise Physiology, Faculty of Exercise, Tehran University, Tehran, Iran دانشگاه تهران Rahman Soori رحمان سوری 5200319475328460053302 5200319475328460053302 No Dept. of Exercise Physiology, Faculty of Exercise, Tehran University, Tehran, Iran دانشگاه تهران Ali Asghar Ravasi علی اصغر رواسی 5200319475328460053303 5200319475328460053303 No Dept. of Exercise Physiology, Faculty of Exercise, Tehran University, Tehran, Iran دانشگاه تهران Hossein Mostafavi حسین مصطفوی 5200319475328460053304 5200319475328460053304 No Dept. of Physiology and Pharmacology,Faculty of Medicine, Zanjan Universityof Medical Sciences, Zanjan, Iran دانشگاه علوم پزشکی زنجان