fa تاثیر تمرین ورزشی هوازی تناوبی حین همودیالیز بر سطح پلاسمایی هموسیستئین و عملکرد بدنی بیماران همودیالیزی کارآزمایی بالینی Clinical Trials <p><strong><em>Background and Objective:</em></strong> Increased homocysteine levels resulting from renal failure and physical inactivity in hemodialysis patients can put them at risk for cardiovascular diseases. On the other hand, exercise training may have a favorable effect on homocysteine levels and physical performance in these patients. Therefore, the aim of the present study was to investigate the effect of eight weeks of intermittent intradialytic aerobic exercise training on plasma homocysteine levels and physical performance in hemodialysis patients.</p> <p><strong><em>Materials and Methods:</em></strong> In this quasi-experimental study, sixteen hemodialysis patients (with a mean age of 54.75 years) were randomly divided into two equal groups: experimental and control. The experimental group performed intermittent intradialytic aerobic exercise training for 8 weeks, 3 sessions per week, which corresponded to 40 to 45 percent of their maximum heart rate reserve at the first week and reached to 65 to 70 percent during the final week. Homocysteine levels and physical performance were measured before and after the 8 weeks of aerobic exercise training.</p> <p><strong><em>Results:</em></strong> Plasma homocysteine levels (P=0.029) and physical performance parameters including: Gait speed (P=0.001), Chair-rising time for 5 times (P=0.001) and Stair-climbing time (P=0.002) significantly improved in the experimental group after eight weeks of intermittent intradialytic aerobic exercise training.</p> <p><strong><em>Conclusion:</em></strong> <a name="OLE_LINK29">Intermittent intradialytic aerobic exercise training may have a favorable effect on the cardiovascular condition of hemodialysis patients through reducing homocysteine levels and can improve physical performance in these patients. &nbsp;</a></p> <p></p><p></p> Keywords: Hemodialysis, Aerobic exercise, Homocysteine 94 104 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-1015&slc_lang=fa&sid=1 Akram Karimi اکرم کریمی 5200319475328460053347 5200319475328460053347 No Dept. of Exercise Physiology, Shahrekord University, Shahrekord, Iran دانشگاه شهرکرد Akbar Azamian Jazi اکبر اعظمیان جزی azamianakbar@yahoo.com 5200319475328460053348 5200319475328460053348 Yes Dept. of Exercise Physiology, Shahrekord University, Shahrekord, Iran دانشگاه شهرکرد Mohammad Faramarzi محمد فرامرزی 5200319475328460053349 5200319475328460053349 No Dept. of Exercise Physiology, Shahrekord University, Shahrekord, Iran دانشگاه شهرکرد Shahrzad Shahidi شهرزاد شهیدی 5200319475328460053350 5200319475328460053350 No Dept. of Internal Medicine, Isfahan University of Medical Sciences and Health Services, Isfahan, Iran دانشگاه علوم پزشکی شهرکرد Zahra Azamian Jazi زهرا اعظمیان جزی 5200319475328460053351 5200319475328460053351 No Faculty of Medicine, Isfahan University of Medical Sciences and Health Services, Isfahan, Iran دانشگاه علوم پزشکی اصفهان