fa تاثیر هشت هفته تمرین ترکیبی هوازی و مقاومتی بر اختلال قند ناشتا، اختلال تحمل به قند و هموگلوبین گلیکولیزه در بیماران پیش‌دیابتی کارآزمایی بالینی Clinical Trials <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:Times New Roman;"><span style="color:#008080;"><strong><em>Background and Objective:</em></strong></span> Lifestyles comprising of physical inactivity coupled with the prevalence of metabolic syndrome and pre-diabetes are the major global public health challenges. Recently, sport sciences have garnered attention as to find new methods for the prevention and treatment of diabetes. Accordingly, the aim of this study is to evaluate the effect of combined exercise on impaired fasting glucose, impaired glucose tolerance and HbA1c in pre-diabetic patients.<br> <strong><em><span style="color:#008080;">Materials and Methods:</span> </em></strong>30 men with pre-diabetes voluntarily took part in this study and were divided into two groups: pre-diabetes exercise and pre-diabetes control. The pre-diabetes exercise group participated in an aerobic (40 to 70 percent of VO2max) and resistance exercise (50 to 70 percent of 1RM) program for 8 weeks. The control group continued their daily activities and normal life. Changes in the serum levels of fasting glucose, two-hour glucose tolerance and HbA1c were then compared between the groups.<br> <strong><em>Results: </em></strong>At the end of the study, fasting glucose levels, two-hour glucose tolerance and the percentage of HbA1c were significantly improved in the pre-diabetes exercise group. Fasting glucose levels, two-hour glucose tolerance and the percentage of HbA1c did not decrease in the control group.<br> <span style="color:#008080;"><strong><em>Conclusion:</em></strong></span> Aerobic and resistance exercise are effective on impaired fasting glucose, impaired glucose tolerance and glycosylated <a href="https://www.ncbi.nlm.nih.gov/mesh/68006442">hemoglobin A </a>in pre-diabetes patients. This effective method could bring<br> pre-diabetes patients closer to their therapeutic targets regarding FBS, OGTT and glycosylated <a href="https://www.ncbi.nlm.nih.gov/mesh/68006442">hemoglobin A. </a>&nbsp;In this study aerobic and resistance exercise possibly prevent the progression of pre-diabetes and multiple complications of type 2 diabetes. However, further studies are needed to draw firm conclusions.</span></span></p> Prediabetes, Hyperglycemia, Impaired Glucose Tolerance, Glycosylated Hemoglobin A, Aerobic and Resistance Exercises 13 23 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-1044&slc_lang=fa&sid=1 Arsalan Damirchi ارسلان دمیرچی 5200319475328460051849 5200319475328460051849 No Dept. of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Guilan, Rasht, Iran دکترای تخصصی فیزیولوژی ورزشی، استاد دانشکده‌ی تربیت بدنی و علوم ورزشی، دانشگاه گیلان، رشت Hossein Chiti حسین چیتی 5200319475328460051850 5200319475328460051850 No Metabolic Diseases Research Center, Faculty of Medical Sciences, Zanjan University of Medical Sciences, Zanjan فوق تخصص غدد و متابولیسم بزرگسالان، استادیار مرکز تحقیقات بیماری‌های متابولیک، دانشگاه علوم پزشکی زنجان، زنجان Soghrat Faghihzadeh سقراط فقیه‌ زاده 5200319475328460051851 5200319475328460051851 No Dept. of Biostatistics, Faculty of Medical Sciences, Zanjan University of Medical Sciences, Zanjan دکترای تخصصی آمار زیستی، استاد دانشکده‌ی پزشکی، دانشگاه علوم پزشکی زنجان، زنجان Mahmood Hakmai Zanjani محمود حکمی زنجانی mahmoud1ir@yahoo.com 5200319475328460051852 5200319475328460051852 Yes Dept. of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Guilan, Rasht, Iran دانشجوی دکترای تخصصی فیزیولوژی ورزشی، دانشگاه گیلان، رشت