fa بررسی سطح سرمی روی در بیماران مبتلا به بهجت با و بدون علایم چشمی یووییت کارآزمایی بالینی Clinical Trials <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:Times New Roman;"><strong><em><span style="color:#008080;">Background and Objective:</span> </em></strong>Behcet&#39;s syndrome is a chronic vasculitis disease that affects multiple organs, including the eyes. Since the involvement of eyes due to inflammation can lead to blindness, therefore it is important that the identifying factors that are associated with increased inflammation be recognized. In recent years the potential role of mineral elements such as zinc in inflammatory conditions has been suggested. The aim of this study was to evaluate the level of zinc in Behcet&#39;s disease with eye involvement<span dir="RTL">.</span><br> <span style="color:#008080;"><strong><em>Materials and Methods</em></strong>:</span> This cross-sectional study was carried out on 75 patients with Behcet&#39;s disease who were divided into three groups consisting of active uveitis, without uveitis and improved uveitis. Venous blood samples were collected from all patients to measure zinc levels using ELISA. Data were analyzed using SPSS software.<br> <span style="color:#008080;"><strong><em>Results:</em></strong></span> The mean serum zinc level was 130 &plusmn; 89/44 in patients with active uveitis, 147 &plusmn; 92/26 in the group with improved uveitis and 146 &plusmn; 92/24&nbsp; in the control group. In patients with active uveitis serum zinc levels were lower than the other two groups but this difference was not statistically significant.<br> <span style="color:#008080;"><strong><em>Conclusion:</em></strong></span> In this study, there was no significant reduction in serum zinc levels in active uveitis group. Therefore, unlike similar studies, we could not find evidence to claim that Behcet&#39;s disease is associated with zinc deficiency and its effects on the exacerbation of ocular inflammation at least in our patients. Therefore, further studies with a larger population of patients and more accurate methods of measurement can be helpful to elucidate such relation.</span></span></p> Behcet’s disease, Uveitis, Zinc 24 31 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-1045&slc_lang=fa&sid=1 Alireza Sadeghi علیرضا صادقی 5200319475328460051468 5200319475328460051468 Yes Dept.of Rheumatology, Valiasr Hospital, Zanjan University of Medical Sciences, Zanjan, Iran فوق تخصص روماتولوژی، دانشیار گروه داخلی، بیمارستان ولیعصر، دانشگاه علوم پزشکی زنجان، زنجان Maryam Jameshorani مریم جامه شورانی dr.shirinjameshoranizums.ac.ir 5200319475328460051469 5200319475328460051469 No Dept.of Internal Medicine, Metabolic Disease Research Center, Zanjan University of Medical Sciences, Zanjan, Iran متخصص داخلی، فلوی فوق تخصص گوارش، استادیار مرکز تحقیقات متابولیک، دانشگاه علوم پزشکی زنجان، زنجان Shima AKbari شیما اکبری 5200319475328460051470 5200319475328460051470 No Valiasr Hospital, Zanjan University of Medical Sciences, Zanjan, Iran پزشک عمومی، بیمارستان ولیعصر، دانشگاه علوم پزشکی زنجان، زنجان Saeiideh Mazloomzadeh سعیده مظلوم‌ زاده 5200319475328460051471 5200319475328460051471 No Social Determinants of Health Research Center, Zanjan University of Medical Sciences, Zanjan, Iran دکترای تخصصی اپیدمیولوژی، دانشیار مرکز تحقیقات عوامل اجتماعی موثر بر سلامت، دانشگاه علوم پزشکی زنجان، زنجان Ayoub Pezeshki ایوب پزشکی 5200319475328460051472 5200319475328460051472 No Dept. of Nephrology, Valiasr Hospital, Zanjan University of Medical Sciences, Zanjan, Iran فوق تخصص نفرولوژی، دانشیار گروه داخلی، مرکز تحقیقات متابولیک، بیمارستان ولیعصر، دانشگاه علوم پزشکی زنجان، زنجان