fa تعیین الگوی مقاومت آنتی بیوتیکی و agr تایپینگ ایزوله‌های استافیلوکوکوس ارئوس جدا شده از ناقلین بینی در پرسنل بیمارستان شهید بهشتی شهر یاسوج کارآزمایی بالینی Clinical Trials <strong><em>Background and Objective: </em></strong>Based on the important role of nasal carriers of <em>Staphylococcus aureus</em> in hospital settings and their importance in the transmission of bacterium to patients and other personnel, the aim of the present study was to determine the frequency of nasal carriers, antibiotic resistance patterns and genotyping of <em>S. aureus</em> isolated from personnel of Shahid Beheshti hospital in Yasuj city (Iran) using the agr typing method.<br> <strong><em>Materials and Methods:</em></strong> In this cross-sectional study, a total of 347 nasal samples were collected from the healthcare workers of Shahid Beheshti Hospital in order to identify <em>S. aureus</em>. Cefoxitin containing disks and detection of the <em>mec</em>A gene were used for the identification of methicillin resistant isolates. The antimicrobial susceptibility patterns of isolates were tested against 15 different antibiotics using the Disc Agar Diffusion method. The Multiplex-PCR method was used for the agr typing of <em>S. aureus </em>isolates.<br> <strong><em>Results:</em></strong> Ninety-three (26.8%) of personnel were nasal carriers of <em>S. aureus</em>, among them 9 isolates were identified as MRSA. Among agr groups, agrI (40.9%) and agrIII (40.9%) were the prominent genotypes. All of the isolates (100%) were resistant to Penicillin. The resistance rate to erythromycin and co-trimoxazole were 12.9% and 5.38% respectively. Most of the isolates were sensitive to other antibiotics.<br> <strong><em>Conclusion: </em></strong>Based on the low resistance rate of <em>S. aureus</em>, it appears that the eradication of nasal carrier states could be possible. <em>S. aureus</em> agr types I and III have an important role in nasal colonization in comparison to other <em>agr</em> types.<br> &nbsp;<br> &nbsp; Keywords: Staphylococcus aureus, Nasal carrier, Agr type, Antibiotic resistance 91 102 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-1050&slc_lang=fa&sid=1 Yaser Mahmoudi Mourderaz یاسر محمودی مورد راز 5200319475328460053142 5200319475328460053142 Yes Student Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran دانشگاه علوم پزشکی یاسوج Reza Chaman رضا چمن 5200319475328460053143 5200319475328460053143 No Dept. of Community Medicine, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran دانشگاه علوم پزشکی یاسوج Seyed Ali Asghar Malekhosseini سید علی اصغر ملک حسینی 5200319475328460053144 5200319475328460053144 No Student Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran دانشگاه علوم پزشکی یاسوج Asghar Sharifi اصغر شریفی 5200319475328460053145 5200319475328460053145 No Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran دانشگاه علوم پزشکی یاسوج Seyed Abdolhamid Khosravani سید عبدالمجید خسروانی 5200319475328460053146 5200319475328460053146 No Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran دانشگاه علوم پزشکی یاسوج Mohammad Taher Rezanejad محمد طاهر رضا نژاد 5200319475328460053147 5200319475328460053147 No Student Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran دانشگاه علوم پزشکی یاسوج Maryam Hassani مریم حسنی 5200319475328460053148 5200319475328460053148 No Student Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran دانشگاه علوم پزشکی یاسوج Reza Mohammadi رضا محمدی 5200319475328460053149 5200319475328460053149 No Medicinal Plants Research Center, Yasuj University of Medical Sciences, Yasuj, Iran دانشگاه علوم پزشکی یاسوج Seyed Sajad Khoramrooz سید سجاد خرم روز khoramrooz@gmail.com 5200319475328460053150 5200319475328460053150 No Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran دانشگاه علوم پزشکی یاسوج