fa بررسی میانگین سطح سرب موجود در خون بند ناف نوزادان با وزن طبیعی در مقایسه با نوزادان کم وزن کارآزمایی بالینی Clinical Trials <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:Times New Roman;"><span style="color:#008080;"><strong><em>Background and Objective</em></strong>:</span> Some changes in newborns growth indices are related to several risk factors; though, a distinct etiology is unknown. Due to the available evidence about highly concentrated levels of lead in our province particularly in comparison to non-contaminated regions, this study was designed to evaluate the relationship between lead levels of umbilical cord blood and newborns birth weight variations in Zanjan, Iran.<br> <span style="color:#008080;"><strong><em>Materials and Methods</em></strong>:</span> 300 newborns were enrolled in this case-control study in Zanjan province. Cord blood samples were obtained&nbsp; from 150 low birth weight (LBW) infants (birth weight lower than 2500 gr) as the case group, and &nbsp;150 normal weight infants (weight= 2500-4000 gr.) as the control group. The blood lead level was measured by atomic absorption spectrophotometry. The collected data were analyzed using independent t-test.<br> <span style="color:#008080;"><strong><em>Results</em></strong>:</span> Umbilical cord blood lead level was significantly high in LBW newborns (79.17&plusmn;37.10 mg/L) in comparison with the control group (73.4&plusmn;42.9 mg/L). there was not this type of relationship(raised mean level of umbilical cord blood lead in LBW newborns compared to normal weight newborns)in newborn groups who distributed based on mother&rsquo;s age and education level variables but there was significant statistical differences in mean level of lead in both these groups in according with gender variable.<br> <span style="color:#008080;"><strong><em>Conclusion:</em></strong></span> High blood level of lead in cord blood samples can potentially be considered as one of the reasons for LBW. </span></span></p> Lead, Umbilical cord blood, Birth weight 98 105 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-1062&slc_lang=fa&sid=1 Asghar Marzban اصغر مرزبان 5200319475328460051398 5200319475328460051398 No Dept of Pediatrics, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran دانشگاه علوم پزشکی زنجان، زنجان Roha Rouhani روجا روحانی 5200319475328460051399 5200319475328460051399 No Dept of Pediatrics, Emam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran دانشگاه علوم پزشکی مازندان، ساری Ramezan Fallah رمضان فلاح 5200319475328460051400 5200319475328460051400 No Dept of Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran دانشگاه علوم پزشکی زنجان، زنجان Masoud Asadi-Khiavi مسعود اسدی خیاوی masadi@zums.ac.ir 5200319475328460051401 5200319475328460051401 Yes Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran دانشگاه علوم پزشکی زنجان، زنجان