en هم‌زیستی تومور دستگاه گوارش و کولیت اولسراتیو در بیمار مبتلا به سوء هاضمه و رکتراژیا: گزارش موردی Clinical Medicine Clinical Medicine گزارش موردی Case Report Article <p style="text-align: justify;"><span style="font-family:times new roman;"><span style="font-size:14px;"><span style="color:#008080;"><strong>Case presentation: </strong></span>A 32-year-old man with dyspepsia and rectorrhagia dating back 3 weeks underwent endoscopy and colonoscopy. Upper GI endoscopy revealed a 2&times;2cm submucosal lesion at the gastric body. Endoscopic ultrasonography confirmed GIST and surgery was recommended. Colonoscopy diagnosed left side inflammatory bowel disease (IBD) (ulcerative colitis). Abdominal CT scan and sonography had no apparent abnormality. The pathology report confirmed low grade, spindle type gastrointestinal stromal tumor (GIST). Treatment was started with oral Mesalazine and Asacol enema. As the abdominal and pelvic CT showed no metastasis, a complete surgical resection of the tumor was performed and in a 6-month follow up, the patient had no problem.<br> <span style="color:#008080;"><strong>Discussion: </strong></span>IBD patients are at an increased risk of malignancy due to chronic inflammatory state and the use of immunomodulator agents. Thus, the risk of malignancies at the beginning of the disease is low and its occurrence is rare.&nbsp; The most common cancer in such patients is adenocarcinoma and GIST is somehow rare, with a small number reported in literature. Since the presence of GIST is not related to disease activity, it should be considered in differential diagnosis in patients with controlled IBD who are still symptomatic.</span></span></p> GIST, IBD, Ulcerative Colitis 51 54 http://journal.zums.ac.ir/browse.php?a_code=A-10-3577-5&slc_lang=en&sid=1 Ahmad Hormati احمد حرمتی hormatia@yahoo.com 5200319475328460054466 5200319475328460054466 No Gastroenterology and Hepatology Disease Research Center, Qom University of Medical Sciences, Qom, Iran مرکز تحقیقات بیماری های گوارش وکبد دانشگاه علوم پزشکی قم Seyed Saeed Sarkeshikian سید سعید سرکشیکیان ss_sarkeshik@hotmail.com 5200319475328460054467 5200319475328460054467 No Gastroenterology and Hepatology Disease Research Center, Qom University of Medical Sciences, Qom, Iran مرکز تحقیقات بیماری های گوارش وکبد دانشگاه علوم پزشکی قم Faezeh Alemi فائزه عالمی faezeh.alemi@gmail.com 5200319475328460054468 5200319475328460054468 No Gastroenterology and Hepatology Disease Research Center, Qom University of Medical Sciences, Qom, Iran مرکز تحقیقات بیماری های گوارش وکبد دانشگاه علوم پزشکی قم Abolfazl Iranikhah ابوالفضل ایرانی خواه hormatia@yahoo.com 5200319475328460054469 5200319475328460054469 No Gastroenterology and Hepatology Disease Research Center, Qom University of Medical Sciences, Qom, Iran مرکز تحقیقات بیماری های گوارش وکبد دانشگاه علوم پزشکی قم Mahdieh Ghodoosi مهدیه قدوسی mghodosi12@yahoo.com 5200319475328460054470 5200319475328460054470 No Dept.of Pathology, Qom University of Medical Sciences, Qom, Iran مرکز تحقیقات بیماری های گوارش وکبد دانشگاه علوم پزشکی قم Mohammad Gharehbeglou محمد قره بیگو m.gharehbeglou@yahoo.com 5200319475328460054471 5200319475328460054471 No Gastroenterology and Hepatology Disease Research Center, Qom University of Medical Sciences, Qom, Iran مرکز تحقیقات بیماری های گوارش وکبد دانشگاه علوم پزشکی قم Maryam Jameshorani شیرین جامه شورانی dr.shirinjameshorani@yahoo.com 5200319475328460054472 5200319475328460054472 No Dept.of Gastroenterolog,Valiasr Hospital, Zanjan University of Medical Sciences, Zanjan, Iran متخصص داخلی، مرکز تحقیقات بیماری های متابولیک دانشگاه علوم پزشکی زنجان، زنجان، ایران Mohammad Reza Ghadir محمدرضا قدیر ghadir1968@gmail.com 5200319475328460054473 5200319475328460054473 Yes Gastroenterology and Hepatology Disease Research Center, Qom University of Medical Sciences, Qom, Iran مرکز تحقیقات بیماری های گوارش و کبد دانشگاه علوم پزشکی قم، قم، ایران