en تآثیرتوام مصرف شنبلیله و آموزش تدابیر تغذیه مبتنی بر طب سنتی ایران بر کاهش FBS، HgA1C ، BMI و دور کمر بیماران دیابت نوع دو: یک کارآزمایی دو عاملی تصادفی Clinical Medicine Clinical Medicine کارآزمایی بالینی Clinical Trials <p style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:times new roman;"><span style="color:#008080;"><strong>Background and Objective</strong><strong>:</strong></span> Diabetes mellitus (DM) is one of the most common metabolic disorders that cause a high annual cost of patients care and health services in a society. &nbsp;Given the fact that DM management is very important, the present study aims to investigate the effect of combined therapy with fenugreek and nutrition training based on Iranian traditional medicine on FBS, HgA1c, BMI, and waist circumference in type 2 diabetic patients.<br> <span style="color:#008080;"><strong>Materials and Methods: </strong></span>This randomized double blinded clinical trial was conducted on patients with type 2 diabetes in Tehran (Iran) during 2017. Patients were randomly divided into four groups, including: G1 [fenugreek powder (10g/two times per day) with nutrition training), G2 [wheat flour (placebo) with nutrition training), G3 [fenugreek powder (10g/two times per day) without nutrition training], and G4 [wheat flour (placebo) without nutrition training].&nbsp;<br> <span style="color:#008080;"><strong>Results: </strong></span>This study was done on 125 patients (43% male and 57% female). There was no significant difference in demographic characteristics of all groups. The mean of FBS in G1, G2, G3 and G4 significantly decreased by 62, 12, and 23 units, respectively (<em>P</em><0.001). The mean of HbA1c in groups G1, G2, and G3 declined by 0.77, 0.31 and 0.5 units, respectively. The mean of BMI in groups G1, G2, and G3 decreased by 1.38, 0.82 and 0.89 units, respectively. Furthermore, waist circumference reduced in all of three groups by 7.11, 3.8 and 3.18 units, respectively. There was no significant change in mean value of these parameters in G4 group.&nbsp;&nbsp;<br> <span style="color:#008080;"><strong>Conclusion: </strong></span>Given the positive effect of fenugreek and nutrition training on FBS, HbA1c, BMI, and waist circumference, it can be suggested for blood glucose control in diabetic patients. Interestingly, combined therapy with fenugreek and nutrition training was more effective in reducing blood glucose, indicating the importance of this combined therapy for blood glucose control in DM patients.&nbsp;</span></span></p> Fenugreek, Type 2 Diabetes, Nutrition training, Iranian traditional medicine 37 42 http://journal.zums.ac.ir/browse.php?a_code=A-10-4665-1&slc_lang=en&sid=1 Seyyedeh Seddigheh Hassani سیده صدیقه حسنی Sshassani75@yahoo.com 5200319475328460054457 5200319475328460054457 No Dept. of Iranian Traditional Medicine, Faculty of Medicine, Shahed University, Tehran, Iran گروه طب سنتی ایران، دانشکده پزشکی، دانشگاه شاهد، تهران، ایران Arezodar Fallahi آرزودار فلاحی 5200319475328460054458 5200319475328460054458 No Dept.of Cardiology, Faculty of Medicine, Shahed University, Tehran, Iran Seyyed Saeid Esmaeili سیدسعید اسماعیلی Dr.esmaeili@chmail.ir 5200319475328460054459 5200319475328460054459 Yes Dept. of Iranian Traditional Medicine, Faculty of Medicine, Shahed University, Tehran, Iran گروه طب سنتی ایران، دانشکده پزشکی، دانشگاه شاهد، تهران، ایران Mohammad Gholami Fesharaki محمد غلامی فشارکی Mohammad.gholami@modares.ac.ir 5200319475328460054460 5200319475328460054460 No Dept. of Biostatistics, Faculty of Medical sciences, Tarbiat Modares University, Tehran, Iran گروه آمار زیستی ، دانشکده علوم پزشکی، دانشگاه تربیت مدرس، تهران، ایران