other ارزیابی دورکنندگی اسانس کاکوتی بر خون خواری آنوفل ماکولی‌پنیس در شهرستان زنجان مقاله پژوهشی Original Research Article <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:times new roman;"><span style="color:#008080;"><strong><em>Background and Objective</em>: </strong></span>Anopheles maculipennis is one of the most important species of mosquito that can cause serious public health problems worldwide and applying insecticides and synthetic repellents are the current methods used for its control. The continuous application of these chemicals increases the probability of resistance, reduces insecticide efficiency and causes environmental problems. Therefore, introducing alternative substances (especially natural repellents) to control programs is necessary. The aim of this study was to compare the repellency effect of Ziziphoratenuior essential oil (EO) with DEET.<br> <span style="color:#008080;"><strong><em>Materials and Methods</em></strong>:</span> <em>Ziziphoratenuior </em>was collected from Zanjan and its EO was extracted from dried leaves via a hydro-distillation process. The chief components of the essential oil were identified through the GC-mass method and serial dilutions of the essential oil and DEET were prepared. Adult <em>An. Maculipennis&rsquo;</em> were collected and kept in a laboratory. Contact bioassays were conducted by 9 volunteers, through a single-blind study where their arms were impregnated with repellent solutions. Non-blood fed female mosquitoes were exposed to different doses of repellents. The effective doses of 50% (ED₅₀) and 90% (ED₉₀) and duration of repellency were determined for each repellent.<br> <span style="color:#008080;"><strong><em>Results: </em></strong></span>Thymol, geraniol and carvacrol are the chief components of <em>Ziziphora </em>EO and form 36.2%, 11.16% and 4.9% of it, respectively. The ED50 and ED90 for this EO against <em>An. Maculipennis </em>were 1.7 and 3.67 mg/cm², respectively. A 30% <em>Ziziphora</em>solution prevented biting for 240 minutes. The response of <em>An. Maculipennis </em>to <em>Ziziphora </em>EO in high doses was similar to that of DEET, however, this response differed in doses lower than 1 mg/cm².<br> <span style="color:#008080;"><strong><em>Conclusion</em></strong>:</span> <em>Ziziphora </em>essential oil 30% solution has similar repellency effect to DEET and can prevent biting of <em>An. Maculipennis </em>for 240 minutes. Synergists could be added to increase its effectiveness and electrophysiologic studies could determine the mechanism of action of thymol and carvacrol at molecular levels.</span></span></p> Anopheles maculipennis, Ziziphora essential oil, Repellents, DEET, Ziziphoratenuoir 96 108 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-1099&slc_lang=other&sid=1 Mohammad Bagher Ghavami محمد باقر قوامی Ghavami@zums.ac.ir 5200319475328460049802 5200319475328460049802 Yes Dept. of Medical Entomology & Vector Control, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran دانشگاه علوم پزشکی زنجان، زنجان، ایران Sakineh Khoeini سکینه خوئینی 5200319475328460049803 5200319475328460049803 No Dept. of Medical Entomology & Vector Control, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran دانشگاه علوم پزشکی زنجان، زنجان، ایران Soghrat Faghih Zadeh سقراط فقیه زاده 5200319475328460049804 5200319475328460049804 No Dept of. Statistics and Social Medicine, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran دانشگاه علوم پزشکی زنجان، زنجان، ایران