en کیفیت زندگی در بیماران پسوریازیس و ارتباط آن با شدت بیماری Clinical Medicine Clinical Medicine مقاله پژوهشی Original Research Article <div style="text-align: justify;"><span style="color:#008080;"><strong>Background & Objective:</strong></span> &nbsp;Psoriasis is a chronic and relapsing disease with a prevalence of 2%. Since it is a chronic and non-fatal skin disease, its impact on quality of life in patients is underestimated compared to other diseases. This study points out to the importance of the quality of life in these patients and their correlation with disease severity.<br> <strong><span style="color:#008080;">Materials & Methods:</span></strong> &nbsp;Quality of life of psoriasis patients was assessed by using the Dermatology Life Quality Index (DLQI) and psoriasis severity was measured, using Psoriasis Area Severity Index (PASI). DLQI were compared regarding age, gender and affected areas in patients.<br> <span style="color:#008080;"><strong>Results: </strong></span>&nbsp;Among 135 patients, 67 (49.6%) were male and 68 (50.4%) were female. The mean age of subjects was 41.49&plusmn;15.43 years (ranging from 17 to 83 years). The mean DLQI score was 10.73&plusmn;7.3 (ranging from 0 to 26). Independent t-test showed that the mean DLQI score was significantly greater in women than men (<em>P</em>=0.031) Spearman test showed positive correlation between DLQI and age as well as PASI and DLQI.<br> <span style="color:#008080;"><strong>Conclusion: </strong></span>&nbsp;Results of this study showed a positive and significant correlation between PASI score and quality of life of patients, which implies that with increasing the severity of the disease, the effect of psoriasis on patients&#39; quality of life increases as well.</div> Psoriasis,Quality of life,Dermatology, 1 5 http://journal.zums.ac.ir/browse.php?a_code=A-10-4970-1&slc_lang=en&sid=1 Fakhrozaman Pezeshkpoor فخرالزمان پزشکپور 5200319475328460054184 5200319475328460054184 Yes Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Naghmeh Zabolinejad نغمه زابلی‌نژاد zabolinejadng@mums.ac.ir 5200319475328460054185 5200319475328460054185 No Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Faezeh Golnouri فائزه گل‌نوری 5200319475328460054186 5200319475328460054186 No Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Shatila Torabi شاتیلا ترابی 5200319475328460054187 5200319475328460054187 No Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Jamile Abed جمیله عابد 5200319475328460054188 5200319475328460054188 No Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran