en Clinical Medicine Clinical Medicine مقاله پژوهشی Original Research Article <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:Times New Roman;"><span style="color:#ffffff;"><strong><span style="background-color:#008080;">Background and Objective:</span></strong></span> Post-stroke fatigue is a troublesome symptom and a common complaint of stroke patients. The purpose of this study was to investigate the psychometric features of the Persian version of the FIS (FIS-P) administered to Iranian stroke patients<span dir="RTL">.</span><br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">Materials and Methods:</span></strong></span> In this cross-sectional methodological study, the psychometric properties of the Persian version of the FIS (FIS-P) were examined. The participants were 280 Iranian people (140 healthy adults; 140 stroke patients) who were assessed using the FIS-P, fatigue severity scale (FSS), and SF-36 questionnaire. The content, convergent, and discriminant validity of the FIS-P were evaluated using CVR and CVI, Pearson correlation, and independent-sampling T-tests, respectively. Furthermore, inter-rater reliability and test-retest reliability were assessed via the intra-class correlation coefficient and SEM. The internal consistency reliability was evaluated using Cronbach&rsquo;s &alpha;.<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">Results:</span></strong></span> The results of the CVR for items ranged from 0.6-1, and the CVI of the FIS-P was 0.85. The Pearson correlation measure revealed strong and inverse correlations between FIS-P and FSS and a low to moderate relationship between all subscales of the SF-36 and FIS-P in terms of convergent validity. T-test results showed the discriminant validity of the FIS-P in differentiating between stroke patients and healthy participants. The ICC coefficients for test-retest and inter-rater reliability for the overall scale were 0.991 and 0.984, respectively. Cronbach&rsquo;s &alpha; was 895.<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">Conclusion:</span></strong></span> The strong psychometric properties of the FIS-P indicated its applicability in assessing the impact of fatigue on stroke victim&rsquo;s daily activities and the effectiveness of therapeutic and rehabilitation interventions.</span></span></p> Fatigue, Stroke, Reliability, Validity 111 118 http://journal.zums.ac.ir/browse.php?a_code=A-10-5271-1&slc_lang=en&sid=1 Seyed Hassan Saneii Saneii.H@iums.ac.ir 5200319475328460051695 5200319475328460051695 No Dept. of Basic Sciences of Rehabilitation, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Marzieh Heidari heidariot@gmail.com 5200319475328460051696 5200319475328460051696 No Dept. of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Masoome Zaree MasoomeZaree@gmail.com 5200319475328460051697 5200319475328460051697 No Dept. of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Malahat Akbarfahimi akbarfahmi.m@iums.ac.ir 5200319475328460051698 5200319475328460051698 Yes Dept. of Occupational Therapy, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran