en Clinical Medicine Clinical Medicine مقاله مروری Review Article <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:Times New Roman;">The Coronavirus infectious disease 2019 (COVID-19) has recently emerged as a pandemic and has endangered the lives of thousands of people worldwide. No specific treatment has been identified so far. However, the identification of diagnostic and prognostic factors in patients can be valuable for the application of preventive strategies. Increased platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), prothrombin time (PT), and D-dimer indices have been found in patients with increased inflammation and thrombosis and can lead to heart disease. Also, an increase in these indices is accompanied by worsening of the disease and impairment of the respiratory tract, which necessitates ventilation for the patients eventually. The evaluation of NLR, PLR, and coagulation parameters can be useful for identifying high-risk individuals who need to be intubated. Patient survival will improve by the timely identification and the use of appropriate treatment strategies.</span></span></p> COVID-19, Diagnosis, Inflammation, Lymphocyte, Neutrophil, Platelet 171 174 http://journal.zums.ac.ir/browse.php?a_code=A-10-5310-2&slc_lang=en&sid=1 Forough Nokhostin forogh_nokhostin@yahoo.com 5200319475328460052106 5200319475328460052106 No Dept. of Internal Medicine, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Mehrdad Dargahi MalAmir dr_mehrdad_dargahi@yahoo.com 5200319475328460052107 5200319475328460052107 No Dept. of Pulmonology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Sara Tutunchi tutunchi.sara@yahoo.com 5200319475328460052108 5200319475328460052108 No Dept. of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Hadi Rezaeeyan hadi.rezaeeyan@yahoo.com 5200319475328460052109 5200319475328460052109 Yes High Institute for Education and Research in Transfusion Medicine, Tehran, Iran