en Clinical Medicine Clinical Medicine کارآزمایی بالینی Clinical Trials <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:Times New Roman;"><span style="color:#ffffff;"><strong><span style="background-color:#008080;">Background and Objective:</span></strong></span> Cerebrovascular accidents (CVA) are of the main causes of mortality and morbidity in the world. This study aimed to investigate the two training protocols in patients with acute ischemic stroke (AIS), and their relationship with the patients&rsquo; prognosis.<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">Materials and Methods:</span></strong></span> This experimental study included 45 patients whose ages ranged from 45 to 65 years. Patients were recruited by convenience sampling and purposive method. The participants were categorized into two intervention groups high-intensity anaerobic training (HIT) and continuous aerobic exercise). The control group individuals had no history of exercise. All three scores were assessed at the beginning of the study and after 28 days.<br> SPSS 22 was used to analyze the collected data and the following statistical tests were performed: independent samples t-test, ANOVA and Tukey post hoc test. The level was considered to be 0.05.<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">Results:</span></strong></span> The National Institutes of Health Stroke Scale (NIHSS) score reduced in both exercise groups compared to the controls, in the post-intervention period (frame 9 to 7). The Mini- Mental State Examination (MMSE) score also increased in the continuous exercise group (from 21.93 to 23.4 in the HIT group and from 22.4 to 24.14 in the continuous group), while the <em>Modified Rankin Scale</em> (MRS) score reduced (frame 3 to 2) (<em>P</em>=0.001).<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">Conclusion:</span></strong></span> Performing intermittent exercise over four weeks can improve the overall prognosis quality of CVA patients by reducing the MRS score.</span></span></p> Acute ischemic stroke, Neurological scores, Outcome measure, Type of exercise 215 222 http://journal.zums.ac.ir/browse.php?a_code=A-10-5046-2&slc_lang=en&sid=1 Mahshid Kadkhodaei Khalafi Kadkhodaei.m1350@gmail.com 5200319475328460064078 5200319475328460064078 No Dept.of Exercise Physiology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Leila Simani l.simani62@gmail.com 5200319475328460064079 5200319475328460064079 No Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Maziar Shojaei maziar.shojaei@gmail.com 5200319475328460064080 5200319475328460064080 Yes Dept. of Neurology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mohammadreza Hajiesmaeili drhajiesmaeili@gmail.com 5200319475328460064081 5200319475328460064081 No Anesthesiology Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.