en Health Improvement Strategies Health Improvement Strategies مقاله پژوهشی Original Research Article <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:Times New Roman;"><span style="color:#ffffff;"><strong><span style="background-color:#008080;">Background and Objective:</span></strong></span> Social support is generally accepted to act as a protective factor against stressful situations. However, the extent of its effect on the depression and lifestyle of myocardial infarction (MI) patients is not known. Therefore, the present study aimed to examine the role of perceived social support in predicting major depressive disorder and lifestyle components in MI patients.<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">Materials and Methods:</span></strong></span> This quasi-experimental study was conducted in 2019 on 176 MI patients chosen through the purposive and convenience sampling methods from the Heart Center Hospital of Mazandaran, Iran. The required information was collected by three standard questionnaires, including the social support&nbsp;appraisals (SS-A)&nbsp;scale by Phillips, the Beck Depression Inventory (BDI-II), and Health-Promoting Lifestyle&nbsp;Profile (HPLP-II). Pearson correlation coefficient and canonical correlation coefficient were performed. The significance level in this study was considered as P-value<0.05.<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">Results:</span></strong></span> The findings of the present study indicated that social support could predict depression by 48% and a significant negative correlation was found between social support and depression (r=-0.47, <em>P</em>=0.01). Moreover, social support had a significant impact on lifestyle components and was shown to predict health accountability (R²=0.691, &beta;=0.289), spiritual growth (R²=0.672, &beta;=0.256), stress management (R²=0.285, &beta;=0.122), and interpersonal behavior (R²=0.586, &beta;=0.175). In addition, it affected these factors significantly.<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">Conclusion:</span></strong></span> Providing opportunities for further social support for MI patients paves the way for enhancing health-promoting behaviors and reducing depression in this group of patients.</span></span></p> Depression, Lifestyle, Myocardial Infarction (MI), Perceived social support 223 229 http://journal.zums.ac.ir/browse.php?a_code=A-10-5558-1&slc_lang=en&sid=1 Hossein Mohsenipouya hosseinmohsenipouya@gmail.com 5200319475328460061333 5200319475328460061333 Yes Dept. of Nursing, Faculty of Nursing, Mazandaran University of Medical Sciences, Sari, Iran. Fereshteh Majlessi Dr_f_majlessi@yahoo.com 5200319475328460061334 5200319475328460061334 No Dept. of Health Education and Promotion, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Yadollah Jannati Jannati.yadollah@gmail.com 5200319475328460061335 5200319475328460061335 No Dept. of Nursing, Faculty of Nursing, Mazandaran University of Medical Sciences, Sari, Iran. Sayed Abolhasan Naghibi anaghibi1345@yahoo.com 5200319475328460061336 5200319475328460061336 No Health Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Ali Ghaemian a.ghaemian@mazums.ac.ir 5200319475328460061337 5200319475328460061337 No Dept. of Cardiology, Faculty of Medicine, Cardiovascular Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Alireza Sangani sangany.psycho@gmail.com 5200319475328460061338 5200319475328460061338 No Dept. of Psychology, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran.