en Clinical Medicine Clinical Medicine کارآزمایی بالینی Clinical Trials <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:Times New Roman;"><span style="color:#ffffff;"><strong><span style="background-color:#008080;">&nbsp;Background and Objective:</span></strong></span> SARS COV-2 is a worldwide pandemic disease<strong>.</strong> There is currently no effective cure for this virus, but some types of herbs can be a good choice for reducing its symptoms. There are some reports that <em>Thymus Vulgaris</em> has a high antioxidant compounds effective in strengthening the immune system, as well as anti-virus effects to reduce the respiratory symptoms. Therefore, we speculated that <em>Thymus Vulgaris</em> could be useful for reducing some of the symptoms in patients suffering from COVID- 19.<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">&nbsp;Materials and Methods:</span></strong></span>&nbsp;First, thyme essential oil was prepared and a questionnaire regarding the patients&rsquo; symptoms was designed. Then, 83 patients with COVID-19 were randomly selected and divided into control group and thyme receiving group (TRG). The questionnaire was completed and emphasized to consume 5 mL of the syrup or essential oil three times per day. Finally, one week after the first visit, the questionnaire was completed again to determine the effects of thyme on the mentioned symptoms. Finally, the test results were reviewed and reported.<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">&nbsp;Results:</span></strong></span>&nbsp;The results one week after taking thyme showed that, the fever (p<0.027), dizziness (p<0.003), cough, dyspnea, muscular pain, headache, anorexia, weakness and lethargy, fatigue, and chest wall pain were significantly reduced (p<0.001). Also, BUN (p<0.004), neutrophil count (p<0.001), and calcium (p<0.034) decreased but, lymphocyte count was increased significantly (p<0.001).<br> <span style="color:#ffffff;"><strong><span style="background-color:#008080;">&nbsp;Conclusion:</span></strong></span>&nbsp;Thyme plant which has high antioxidant properties, strengthens the immune system, and induces the antiviral effect could reduce the symptoms of coronavirus; therefore, it is recommended for reducing the symptoms of COVID-19.</span></span></p> COVID-19, Thyme, Thymus Vulgaris, Persian Medicine, Respiratory, 83 91 http://journal.zums.ac.ir/browse.php?a_code=A-10-5620-1&slc_lang=en&sid=1 Saeed Sardari ssardari504@gmail.com 5200319475328460060776 5200319475328460060776 No Dept. of Persian Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Ahmadreza Mobaiend mobaien@zums.ac.ir 5200319475328460060777 5200319475328460060777 No Dept.of Infectious Diseases, Vali-e-asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Leila Ghassemifard l.ghasemifard1893@gmail.com 5200319475328460060778 5200319475328460060778 No Dept. of Persian Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Koorosh Kamali drkamali@zums.ac.ir 5200319475328460060779 5200319475328460060779 No Social Determinants of Health Research Center, Zanjan University of Medical Sciences, Zanjan, Iran Narjes Khavasi nxavasi@zums.ac.ir 5200319475328460060780 5200319475328460060780 Yes Dept. of Persian Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran