en Medical Biology Medical Biology مقاله پژوهشی Original Research Article <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:Times New Roman;"><b><span style="background:#2d7f8f"><span style="color:white">Background & Objective:</span></span><b> </b>&nbsp;</b>Given the critical importance of timely diagnosis and treatment of cesarean scar pregnancy (CSP) and the lack of comprehensive studies in this field, this study was conducted to investigate the relationship between maternal complications following CSP surgery and various demographic and clinical factors.<br> <b><span style="background:#2d7f8f"><span style="color:white"><span style="letter-spacing:-.1pt">&nbsp;Materials & Methods:</span></span></span></b> <span style="letter-spacing:-.1pt">This cross-sectional study analyzed 350 patients who underwent surgical treatment for CSP at Imam Khomeini Hospital in Ahvaz, Iran, from 2014 to 2023. Demographic and clinical data were collected from medical records. Statistical analyses, including chi-square and t-tests, were performed to assess associations between gestational age, uterine scarring patterns, fetal status, and maternal complications such as blood transfusion, hypervascularity, curettage, laparotomy, hysterectomy, and bladder rupture.</span><span style="color:black"><span style="letter-spacing:-.1pt"> </span></span><br> <b><span lang="EN-IN"><span style="background:#2d7f8f"><span style="color:white">Results: </span></span></span>&nbsp;</b><span style="letter-spacing:-.1pt">The mean gestational age at diagnosis was 49.58 &plusmn; 17.07 days. Intrauterine scarring was the most common (68.57%), and 64.29% of fetuses were deceased at diagnosis. Curettage was the primary intervention (84.29%). Higher gestational age was significantly associated with increased need for packed cell transfusion (p<0.001), hypervascularity (p=0.007), and laparotomy (p<0.001). Uterine scarring patterns were significantly associated with packed cell transfusion, hypervascularity, curettage, and laparotomy (p<0.001). Fetal status significantly influenced rates of curettage (p=0.01) and laparotomy (p=0.02). There were no cases of disseminated intravascular coagulation or maternal death.</span><br> <b><span style="background:#2d7f8f"><span style="color:white">Conclusion: </span></span>&nbsp;</b>Gestational age, uterine scarring patterns, and fetal status are significant factors associated with maternal complications in CSP surgery. Early diagnosis and intervention may reduce the risk of severe complications.</span></span></p> Cesarean Section, Postoperative Complications, Gestational Age, Risk Factors 105 113 http://journal.zums.ac.ir/browse.php?a_code=A-10-7201-1&slc_lang=en&sid=1 Mojgan Barati barati_m70@yahoo.com 5200319475328460084295 5200319475328460084295 No Department of Obstetrics and Gynecology, School of Medicine, Fertility- Infertility and Perinatology Research Center. Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Roshan Nikbakht rosnikba@yahoo.com 5200319475328460084296 5200319475328460084296 No Department of Obstetrics and Gynecology, School of Medicine, Fertility Infertility and Perinatology Research Center. Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Sara Masihi s.masihi@yahoo.com 5200319475328460084297 5200319475328460084297 No Department of Obstetrics and Gynecology, School of Medicine, Fertility Infertility and Perinatology Research Center. Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Marjan Zamani Marjanzamaniii3198@gmail.com 5200319475328460084298 5200319475328460084298 Yes Department of Obstetrics and Gynecology, School of Medicine, Fertility Infertility and Perinatology Research Center. Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran