fa بررسی ارتباط رزیستین بند ناف با لپتین، انسولین، اندکس‌های رشدی و درصد چربی نوزادان تازه متولد شده در بیمارستان آیت الله موسوی زنجان در سال1388 مقاله پژوهشی Original Research Article <p style="text-align: justify;"><strong><em>Background and Objective: </em></strong>Resistin is a novel adipokine which may play a role in insulin resistance. In this study we aimed to determine the cord blood resistin, leptin, insulin and maternal serum resistin levels during pregnancy; and to investigate correlation between these metabolic hormones; and also to evaluate their association with newborn growth indices.<br> <strong><em>Materials and Methods:</em></strong> This study was conducted on 80 newborns and their mothers in Mousavi Hospital Zanjan, Iran in 2009. Newborn growth indices including birth weight, height, body mass index (BMI), Ponderal index, Homeostatic Model assessment (HOMA-IR) and their mothers&rsquo; BMI were determined. Resistin, leptin and insulin levels were measured by ELISA.<br> <strong><em>Results:</em></strong> In this study, cord blood resistin levels were higher than serum resistin levels of pregnant mothers (10.77&plusmn;1.53 vs. 7.91&plusmn; 5.71 ng/ml). Moreover, serum resistin levels of mothers&rsquo; did not exhibit any correlation with cord blood resistin, leptin and insulin levels, as well as neonatal anthropometric indices. Meanwhile, there was no significant correlation between cord resistin levels, insulin resistance, fat percentage and newborn growth factors. Cord resistin levels were positively correlated with cord blood leptin levels (r=0.222; p=0.048). Also, there was a significant positive correlation between cord blood leptin and neonatal BMI (r=0.223; p=0.047), Ponderal index (r=0.212; p=0.058), HOMA-IR (r=0.426; p=0.052) and fat percentage (r=0.247; p=0.014).<br> <strong><em>Conclusion:</em></strong> On the basis of the findings,&nbsp; &nbsp;increased cord blood resistin levels may indirectly influence fetal growth through leptin or other cytokine levels. Though, further researches are needed to confirm this matter.&nbsp;</p> Pain, Bleeding, Cesarean, Paracetamol, Diclofenac 1 10 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-574&slc_lang=fa&sid=1 Habib Nazem حبیب ناظم 5200319475328460060131 5200319475328460060131 No Dept. of Biochemistry, Tehran Payam-e-nour University, Tehran, Iran دکترای بیوشیمی بالینی، دانشیار دانشگاه پیام نور مرکز تهران Faranak Sharifi فرانک شریفی 5200319475328460060132 5200319475328460060132 No Metabolic Research Center, Zanjan University of Medical Sciences, Zanjan, Iran فوق تخصص غدد، مرکز تحقیقات بیماری‌های متابولیک زنجان، استاد دانشگاه علوم پزشکی زنجان Seyed Ali Naghi Kazemi سید‌علی‌نقی کاظمی 5200319475328460060133 5200319475328460060133 No Metabolic Research Center, Zanjan University of Medical Sciences, Zanjan, Iran متخصص اطفال، مرکز تحقیقات بیماری‌های متابولیک زنجان، دانشیار دانشگاه علوم پزشکی زنجان Seyed Norodin Mousavinasab سیدنورالدین موسوی نسب 5200319475328460060134 5200319475328460060134 No Metabolic Research Center, Zanjan University of Medical Sciences, Zanjan, Iran دکترای تخصصی آمار زیستی، مرکز تحقیقات بیماری‌های متابولیک زنجان، دانشیار دانشگاه علوم پزشکی زنجان Nasrollah Ghorovghi نصرالله غرقی 5200319475328460060135 5200319475328460060135 No Dept. of Biochemistry, Tehran Payam-e-nour University, Tehran, Iran کارشناسی ارشد بیوشیمی، دانشگاه پیام نور مرکز تهران Soraya Boayni ثریا بوئینی 5200319475328460060136 5200319475328460060136 No Val-e-Asr Hospital, Zanjan University of Medical Sciences, Zanjan, Iran کارشناس ارشد ایمونولوژی، بیمارستان حضرت ولیعصر(عج) زنجان Aliosat Mehhati علی‌اوسط ملتی mellati3000@yahoo.com 5200319475328460060137 5200319475328460060137 Yes Metabolic Research Center, Zanjan University of Medical Sciences, Zanjan, Iran دکترای بیوشیمی، مرکز تحقیقات بیماری‌های متابولیک زنجان، دانشیار دانشگاه علوم پزشکی زنجان