fa تأثیر تمرینات تناوبی با شدت بالا (HIIT) بر سطوح پلاسمایی آدیپونکتین ، مقاومت و حساسیت انسولینی مردان جوان غیر فعال کارآزمایی بالینی Clinical Trials <p>Background and Objective: Adiponectin plays an important role in hyperglycemia, lipolysis, and inflammatory mechanisms. However, mechanisms responsible for the relationship between adiponectin and insulin resistance in response to exercise, still remains unclear. The aim of this study was to determine the effects of a six-week-long high intensity interval training (HIIT) on plasma adiponectin levels, insulin sensitivity, insulin resistance, and &beta;-cells function in sedentary young men. Materials and Methods: Eighteen students voluntarily participated in the study and were randomly divided into two groups: Experimental (n=9, age=24.33 &plusmn;1.41 yr, height=176.22 &plusmn;4.91 cm, weight=72.27 &plusmn;6.59 kg) and Control (n=9, age=23.27 &plusmn;2.01 yr, height=180.22 &plusmn;6.88 cm, weight=76.27 &plusmn;7.33 kg) groups. The test group performed three HIIT sessions per week for 6 weeks. Each session consisted of four to six repeats of maximal sprint running within a 20-m area with 30 s recoveries. Fasting blood samples were collected immediately before and after the exercise protocol. Data were analyzed by dependent and paired t-tests. Results: The results indicates that while plasma adiponectin levels in the experimental group increased significantly (P= 0.047), there was a significant decrease in the percentage of body fat (P= 0.019). There were also a decrease in serum concentrations of insulin, fasting glucose and insulin resistance values as well as an increase amounts of insulin sensitivity and beta cells function. However, these changes were not statistically significant (P>0.05). Conclusion: Our findings show HIIT is a time efficient method for increasing adiponectin levels and reducing body fat. Also, the intensity of exercise as an important factor in the increase in adiponectin levels could be noted.</p> Keywords: High intensity interval training, Adiponectin, Insulin resistance, Insulin sensitivity 1 12 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-684&slc_lang=fa&sid=1 Mohammad Hemmatinafar محمد همتی نفر M_hematinafar@yahoo.com 5200319475328460059639 5200319475328460059639 Yes Dept. of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran Mohammad Reza Kordi محمدرضا کردی 5200319475328460059640 5200319475328460059640 No Dept. of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran Servat Choopani ثروت چوپانی 5200319475328460059641 5200319475328460059641 No Dept. of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran Sirous Choobineh سیروس چوبینه 5200319475328460059642 5200319475328460059642 No Dept. of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran Reza Gharari Arefi رضا قراری عارفی 5200319475328460059643 5200319475328460059643 No Dept. of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran