Journal of Advances in Medical and Biomedical Research

fa مقایسه‌ی تاثیر قطره‌ی میتومایسین Cحین و پس از عمل جراحی در عود، حدت بینایی و فشار داخل چشمی در جراحی ناخنک The Effect of Intra-operative Versus Post-operative Mitomycin C on Recurrent, Visual Acuity and Intraocular Pressure after Pterygium Surgery کارآزمایی بالینی Clinical Trials <p>Background and Objective: Pterygium is a common ocular surface disorder. A number of surgical procedures are used to remove it. The purpose of this study was to compare recurrent, visual acuity and intraocular pressure after pterygium surgery using mitomycin C during and after surgery. Materials and Methods: In this interventional study, 119 patients with indications for pterygium surgery were enrolled and randomly divided into two groups. In the first group, intraoperative 2% mitomycin C was used for 3 min and in the second group, 2% mitomycin C was given four times a day for 2 weeks The patients were followed up for 15 months after the surgery. The data was collected and analyzed by using SPSS software (version 16), and repeated measurement test at a significance level of 0.05. Results: The mean visual acuity showed no significant difference in intraoperative and postoperative mitomycin (P=0.8). Also, the difference in the mean of intraocular pressure between the two groups was not significant (P=0.3). Conclusion: The use of intraoperative mitomycin-C in pterygium surgery was not correlated with visual acuity and intraocular pressure. It is recommended to use mitomycin C in intraoperative methods due to its fewer problems.</p> Keywords: Pterygium, Mitomycin C, Visual acuity, Intraocular pressure 66 73 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-786&slc_lang=fa&sid=1 Reza Rezaei رضا رضایی dr.rezaee@Arakmu.ac.ir 5200319475328460059296 5200319475328460059296 Yes Dept. of Ophthalmology, Arak University of Medical Sciences, Arak, Iran Fahimeh Vali-Zade فهیمه ولی‌زاده 5200319475328460059297 5200319475328460059297 No General Practitioner, Arak University of Medical Sciences, Arak, Iran Arefeh Sadat Ashrafi عارفه سادات اشرفی 5200319475328460059298 5200319475328460059298 No General Practitioner, Arak University of Medical Sciences, Arak, Iran Amir Almasi-Hashiani امیر الماسی حشیانی 5200319475328460059299 5200319475328460059299 No Dept. of Epidemiology, Faculty of Health, Tehran University of Medical Sciences, Tehran, Iran