fa بررسی سروپروالانس هپاتیت B در خانم‌های باردار مراجعه کننده به مراکز بهداشتی درمانی شهرستان زنجان مقاله پژوهشی Original Research Article <p>Background and Objective: Hepatitis B virus is one of the hepadnaviruses which is an important cause of acute and chronic hepatitis, cirrhosis and hepatocellular carcinoma. Currently, prenatal transmission is the most important spreading route of hepatitis B in Iran and probability of its conversion into asymptomatic carrier in newborns of these women is high. Thus, this study was designed in order to have more accurate information about its prevalence among pregnant women in Zanjan city. Materials and Methods: In this cross-sectional descriptive study, from 1317 pregnant women who referred to healthcare centers, 2 mL blood sample was taken and after centrifugation the serums were kept frozen in -20℃. ELISA kit was used for measuring HBs-Ab and Immuno affinity chromatography was used for HBs-Ag measurement. Results: In this study, the prevalence of HBs-Ag and HBs-Ab was 0.4% and 38.4%, respectively. There was no correlation among the HBs-Ag positive individuals, history of jaundice, different age groups, and location. However, a statistically significant relationship was found between education level and positive HBs-Ag, as well as the history of vaccination against hepatitis B and the positive HBs-Ab. Conclusion: According to the results, it seems that parrallel to increase in education and awareness level, especially in pregnant women, the incidence and consequences of the chronic form of this disease has been reduced.</p> Keywords: HBV, HBs-Ag, HBs-Ab, Pregnancy 96 104 http://journal.zums.ac.ir/browse.php?a_code=A-10-4-802&slc_lang=fa&sid=1 َAhmad reza Mobaien احمد رضا مبین amobaien@yahoo.com 5200319475328460059255 5200319475328460059255 Yes Dept. of Infectious Diseases and Tropical Medicine, Zanjan University of Medical Sciences, Zanjan, Iran Farnaz Mohammadian فرناز محمدیان 5200319475328460059256 5200319475328460059256 No Dept. of Obstetrics and Gynecology, Zanjan University of Medical Sciences, Zanjan, Iran Saeedeh Mazloomzadeh سعیده مظلوم‌زاده 5200319475328460059257 5200319475328460059257 No Dept. of Epidemiology, Zanjan University of Medical Sciences, Zanjan, Iran Abdoreza Esmaeilzadeh عبدالرضا اسماعیل‌زاده 5200319475328460059258 5200319475328460059258 No Dept. of Immunology, Zanjan University of Medical Sciences, Zanjan, Iran Rahim Sorouri Zanjani رحیم سروری زنجانی 5200319475328460059259 5200319475328460059259 No Dept. of Microbiology, Zanjan University of Medical Sciences, Zanjan, Iran Sepideh Savabi سپیده صوابی 5200319475328460059260 5200319475328460059260 No Saeed Soleimanipor سعید سلیمانی‌پور 5200319475328460059261 5200319475328460059261 No Fariba Khodami Khosroshahi فریبا خدامی خسرو شاهی 5200319475328460059262 5200319475328460059262 No Bahram Hajikarim بهرام حاجی کریم 5200319475328460059263 5200319475328460059263 No Dept. of Infectious Diseases and Tropical Medicine, Zanjan University of Medical Sciences, Zanjan, Iran