en آیا نوع درد، شدت درد را در افراد مبتلا به مولتیپل اسکلروزیس تغییر می دهد؟ تجزیه و تحلیل طولی با استفاده از معادلات تخمینی کلی Clinical Medicine Clinical Medicine مقاله پژوهشی Original Research Article <p style="text-align: justify;"><span style="font-family:times new roman;"><span style="font-size:14px;"><span style="color:#008080;"><strong>Background & Objective:</strong></span> Pain is a common symptom among people with MS. In the majority of MS patients, pain is chronic in nature, but it can change over time. The objective of this study was to determine if pain type can predict pain severity changes in individuals with MS over time.<br> <span style="color:#008080;">&nbsp;<strong>Materials & Methods:</strong></span> The research method was a longitudinal design that evaluated pain type and severity at baseline and after 3 years of follow up among people with MS. At the beginning of the study a random sample comprising of 188 individuals with MS were recruited. From those, 78 individuals experienced pain included the study. The McGill pain questionnaire and ID-Pain questionnaire were used to assess type of pain. Numeric Rating Scale was used to measure pain severity. McNemar, Cohen&rsquo;s un-weighted Kappa Coefficient, Paired Student t-tests and Generalized Estimating Equations were used to analyze the data.<br> <span style="color:#008080;"><strong>Results: </strong></span>Findings indicated that all pain severity ratings raised on average, though this difference was statistically significant only for lowest pain (<em>P</em>=0.0006). Type of pain did not change in the major part of study sample (<em>P</em>=0.44). Results further indicated that over the follow-up period the lowest pain severity scores were significantly predicted by type of pain (<em>P</em><0.05), while the pain ratings in worst pain severity was not predicted by the type of pain.<br> <span style="color:#008080;"><strong>Conclusion:</strong></span> Results of the current study help for better understanding of the pain type and severity changes over time among patients with MS.</span></span></p> Multiple sclerosis, Neuropathic pain, Pain stability, Generalized estimating equation 9 15 http://journal.zums.ac.ir/browse.php?a_code=A-10-4557-1&slc_lang=en&sid=1 Shahnaz Shahrbanian شهناز شهربانیان shahrbanian@gmail.com 5200319475328460053925 5200319475328460053925 Yes Dept. of Physical & Occupational Therapy, Faculty of Medicine, McGill University, Montreal, Canada Pierre Duquete پیره داکوته pierre.duquete@ssss.gouv.qc.ca 5200319475328460053926 5200319475328460053926 No Notre-Dame Hospital (CHUM), University of Montreal, Montreal, Canada Nancy Mayo نانسی مایو nancy.emayo@clinepi.mcgill.ca 5200319475328460053927 5200319475328460053927 No Dept. of Clinical Epidemiology, McGill University Health Center, Royal Victoria Hospital, Montreal, Canada