en Clinical Medicine Clinical Medicine گزارش موردی Case Report Article <p style="text-align: justify;"><span style="font-size:16px;"><span style="font-family:Times New Roman;">Leishmaniasis is a worldwide vector-borne disease. The Cutaneous form of this disease leaves chronic wounds on the patient&#39;s skin. The purpose of this study was to treat cutaneous leishmaniasis woundsusing <em>Lucilia serricata</em> larvae. Leishman&rsquo;s body was confirmed and<em> Leishmania</em> <em>major</em> was identified using PCR test in the samples of three patients in health center of Andimeshk County, southwest Iran during 2019-2020. The patients signed an informed consent form to receive maggot therapy. Five to ten sterile 1st instar larva of <em>L. serricata</em> per cm²wound were inserted directly on the wounds in 48-hours intervals and bandaged with sterile saline gauze. Cutaneous leishmaniasis wounds were free of purulent secretion within 9-12 days. After 30- 45 days of treatment; the wounds were healed entirely without leaving scar tissues. The results showed&nbsp;larvae of <em>L</em>. <em>sericata</em>&nbsp;can significantly improve wound healing rate but it is recommended to evaluate this biotherapy method in more patients.</span></span> <p></p></p> Maggot, Biotherapy, Cutaneous Leishmanisis 69 72 http://journal.zums.ac.ir/browse.php?a_code=A-10-5664-1&slc_lang=en&sid=1 Asghar Nasiri na30ri.a@gmail.com 5200319475328460066868 5200319475328460066868 No Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Elham Jahanifard jahanifard-e@ajums.ac.ir 5200319475328460066869 5200319475328460066869 No Dept. of Medical Entomology and Vector Control, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Mona Sharififard sharififard-m@ajums.ac.ir 5200319475328460066870 5200319475328460066870 Yes Dept. of Medical Entomology and Vector Control, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Reza Arjmand arjmand.reza@yahoo.com 5200319475328460066871 5200319475328460066871 No Dept. of Medical Parasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Sima Rasai Rasai-s@yahoo.com 5200319475328460066872 5200319475328460066872 No Dept. of Dermatology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Tahmaseb Haeri 5200319475328460066873 5200319475328460066873 No Health Center of Andimeshk County, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran