Volume 22, Issue 91 (4-2014)                   J Adv Med Biomed Res 2014, 22(91): 25-38 | Back to browse issues page

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Dehghan P, Pourghassem Gargari B, Faghfoori Z, Salekzamani S, Jafarabadi M A. Comparative Effect of Inulin and Oligofructose-Enriched Inulin on Glycemic Indices and Blood Pressure in Women with Type 2 Diabetes: A Randomized Clinical Trial. J Adv Med Biomed Res 2014; 22 (91) :25-38
URL: http://journal.zums.ac.ir/article-1-2556-en.html
1- Student Research Committee, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran
2- Dept. of Biochemistry & Diet Therapy, Nutrition Research Center, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran. , bahrampg@yahoo.com
3- Student Research Center, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.
4- Dept. of Statistic and Epidemiology, Faculty of Health, Tabriz University of Medical Sciences.
Abstract:   (180077 Views)

Background and Objective: There is a high prevalence of chronic diseases such as type 2 diabetes in most populations. Therefore, interest in use of functional foods for the control of such diseases is of importance. The present study was designed to compare the effects of inulin and oligofructose-enriched inulin on glycemic indices and blood pressure in women with type 2 diabetes. Materials and Methods: In this clinical trial, 76 women with type 2 diabetes were randomly assigned to one of the three groups. The intervention groups received 10g/d oligofructose-enriched inulin (n=27) or inulin (n=24) and the control group (n=25) received 10g/d maltodextrin for 8 weeks. Dietary intakes, anthropometric measurements, glycemic index and blood pressure were measured at the baseline and after 8 weeks of supplementation. Data were analyzed using SPSS software (version11.5). Paired, ANOVA and ANCOVA were used to compare quantitative variables. Results: At the end of the study significant decrease was observed in energy and carbohydrate intake, anthropometric indices, systolic blood pressure, HbA1c and serum insulin in intervention groups compared with the placebo group (P<0.05). Decrease in carbohydrate intake (16.50%), serum insulin (18.50%) and insulin sensitivity index (QUICKI) (16.70%) was significant in inulin as compared to oligofructose-enriched inulin group. Conclusions: Probably, supplementation of diabetic women with fructans in particular with long chain fructan (inulin) via improving food intake, glycemic indices and blood pressure contributes to the management of type 2 diabetes.

Full-Text [PDF 254 kb]   (160120 Downloads)    
Type of Study: Clinical Trials |
Received: 2014/03/5 | Accepted: 2014/03/5 | Published: 2014/03/5

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2025 CC BY-NC 4.0 | Journal of Advances in Medical and Biomedical Research

Designed & Developed by : Yektaweb