diseases and emphasis on using nondrug treatments, this study was performed to assess the effect of wheat germ on lipid profile reduction among hyperlipidemia and normolipidomia students. Materials and Methods: 108 volunteer students in the age range of 21.33±2.15 years old (74 normolipidemics, 34 hyperlipidemics) were entered to the study. In addition to their typical diet, these students were asked to take a 30- gram wheat germ in their daily diet for 4 weeks. Hyperlipidemia and normolipidomia participants were determined based on National Cholesterol Education Program Adult Treatment Panel 3 (NCEPATP3) guidelines. Anthropometric and metabolic measurements, calorie and mineral intakes, before and after the intervention were taken and analyzed using paired t-test (SPSS version 19). Results: In the wheat germ group, total cholesterol, triglycerides and VLDL (p=0.001) significantly reduced to 10.5, 19 and 20%, respectively. 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