Background and Objective: Eosinophilic gastroenteritis is a rare disease with eosinophilic infiltration of the wall of the gastrointestinal tract, especially in stomach and small bowel. The etiology of the disease is unknown.
Case Report: A 61 year man was admitted because of epigastric pain for 10 days with burning quality with an increase after each meal. Laboratory tests showed mild leukocytosis with 5% eosinophilia, mildly elevated ESR & CRP and serum IgE at upper normal limit. Increased mucosal thickness was shown in posterior gastric wall and the descending part of duodenum seemed narrow with thick irregular wall. CT scan and esophago-gastro-duedenoscopy revealed gastric distention and erythema in D1 region with luminal narrowing. Pathology report from D1, showed inflammatory infiltration with eosinophilia in lamina propria. The patient was treated with oral prednisolone. All complaints and manifestations disappeared soon after treatment and the radiologic studies showed normal image.