دوره 28، شماره 130 - ( 7-1399 )                   جلد 28 شماره 130 صفحات 295-291 | برگشت به فهرست نسخه ها


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Rashidi M, Ahmadi A, Ramazanzadeh R, Noori B, Shafiee F. Probiotic Enterococcus durans Interference with Oral Candida albicans Adhesion: An in vitro Study. J Adv Med Biomed Res 2020; 28 (130) :291-295
URL: http://journal.zums.ac.ir/article-1-6055-fa.html
Probiotic Enterococcus durans Interference with Oral Candida albicans Adhesion: An in vitro Study. Journal of Advances in Medical and Biomedical Research. 1399; 28 (130) :291-295

URL: http://journal.zums.ac.ir/article-1-6055-fa.html


چکیده:   (142677 مشاهده)
Background and Objectives: Candida species is one of the commensal microorganisms and a member of the oral cavity normal flora. In addition, Candida albicans is a microbiologic member of the oral cavity in children with dental caries. Currently, use of probiotics as a new biologic technique has attracted attention in order to prevent and control diseases. Enterococcus durans has shown useful antioxidative properties and antibacterial and probiotic characteristics. The aim of this study was to evaluate the effect of probiotic Enterococcus durans on adhesion of Candida albicans in in vitro.
 
Materials and Methods: In this in vitro study, the standard strain bacteria of probiotic E. durans (ATCC 6056) and Candida albicans (PTCC5027) and 10 clinical samples of Candida albicans is provided. The adhesive inhibition of Candida albicans via microtiter plate was tested.  Data were analyzed with repeated measure model. Statistical significance was set at P<0.01
Results: This study showed that, Mean OD620 nm were in range of 0.45 to 0.49 and for OD490 nm were 0.33. Therefore, in presence of the probiotic strain, the biofilm of Candida albicans adhesion were reduced.
Conclusion: The first step in infection process is attachment and the adhesion                  of Candida albicans can be prohibited by use of probiotic such as E. durans.
متن کامل [PDF 311 kb]   (155363 دریافت)    
نوع مطالعه: مقاله پژوهشی | موضوع مقاله: Clinical medicine
دریافت: 1399/3/19 | پذیرش: 1399/4/31 | انتشار: 1399/6/31

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