Background and Objective: Myocardial infarction (MI) also known as heart attack is the irreversible death (necrosis) of the heart muscle cells due to lack of oxygen delivery to the heart muscle tissue as blood flow is diminished or stopped in the coronary passage of the heart. Moreover, the associated severe myocardial loss is the main cause of death. The main objective of this study was to explore the clinical importance of inflammatory markers (chemerin and resistin) as well as cardiac enzymes including lactate dehydrogenase (LDH).
Methods: In order to reach these goals, the study included 120 subjects, 60 of them were patients whom diagnosed with myocardial infarction based on the patient’s condition, symptoms, and electrocardiogram (ECG) with an average age of (59.31±1.64) years, and other 60 subjects were healthy used as control group with an average age of (37.30±2.10) years.
Results: This study was conducted in the Cardiac Care Unit/Baqubah Teaching Hospital in Diyala governorate/ Iraq. The results of the study showed there was a significant decrease (P<0.001) in the levels of chemerin and resistin, while there was a significant increase (P<0.001) in the level of troponin I, LDH, CK-MB and AST.
Conclusion: As conclusion the levels of chemerin and resistin in patients group were decreased significantly after admitted into Cardiac Care Unit and receive the treatment. So the decrease of chemerin and resistin levels in patients group may be used as indictor in response to treatment.
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