Background and Objective: Epilepsy is the most common neurological disorder after stroke. The aim of the present study was to evaluate the effect of hydroalcoholic extract of Heracleum persicum on pentylenetetrazol (PTZ) - induced seizure in mice. Materials and Methods: In this study, 30 male mice were divided into five groups. 30 minutes after IP administration with different doses of extract (75,150, 300, 600mg/kg), PTZ (80 mg/kg) was injected to animals and they were instantly transferred to a special cage. Consequently, the convulsive behaviors of the mice were recorded by a camera as long as 20 minutes and the data were converted into seconds to be considered for analysis. Results: The results indicated that hydroalcoholic extract of Heracleum persicum has a significant effect on threshold tonic seizure in doses of 150 mg/kg, 300mg/kg and 600 mg/kg. In clonic phase, threshold increased slightly with an increase in doses of extract. In tonic-clonic phase, threshold increase was significant only in doses of 150 mg/kg and 900 mg/kg. This extract significantly decreased seizure duration time both in tonic and tonic-clonic phases upon dose increasing. Conclusion: The results of the present study imply that injection of hydro-alcoholic extracts of Heracleum persicum led to anticonvulsant activity. This extract augmented the onset of different seizure phases while reduced duration of tonic and tonic-clonic phases.

Background and Objective: Meconium Stained Amniotic Fluid (MSAF) is a common finding in term and post term pregnancies which has been taken into account as an unfavorable predictor of fetal and neonatal outcome. The aim of this study was to identify some maternal risk factors and neonatal complications in term pregnancies with meconium stained and clear amniotic fluid in Rasht Al Zahra Hospital during 2010-2011. Materials and Methods: Throughout this cross-sectional analytic study, 300 pregnant women and term neonates with MSAF and 300 pregnant women and term neonates with clear amniotic fluid were studied in Rasht Al Zahra Hospital from 2010 to 2011. The collected data were processed and analyzed by SPSS-16 software. Results: The most common maternal risk factors and neonatal complications which associated with MSAF were maternal gravidity and parity, mode of delivery, gestational age, Apgar score, neonatal birth weight and admission days. Maternal and neonatal infections were not significantly different in two groups. Conclusion: The findings indicate that MSAF was significantly associated with lower maternal gravidity and parity, higher incidence of cesarean section rates, lower 1 minute Apgar scores and higher gestational age, neonatal birth weight and admission days but there was no association between MSAF and chorioamnionitis.

Background and Objective: The verse of "shifaa" (and We send down, of the Quran, that which is a healing and a mercy to the believers and the unbelievers it increases not, except in loss Al- Israa:82) is the leading document for Quranic and medical interdisciplinary researches. Despite its popularity, it has not found its particular grounding amongst us. This research was an endeavor to enlighten the ways in order to improve the quantity and quality of medical references to this verse, to put forward the lexical relationship concerning the elements of the verse, and to bring about a novel method of documentation and referencing as pertinent to this verse. Materials and Methods: This research yielding a conceptual analysis of the words in Shifaa verse and their coherence and connection based on the morphology of words and implementation of contrastive analysis takes into account the register of the verse and reconsiders its very delicate and subtle aspects. Thereby, this research puts forward some of the infrastructure in the interdisciplinary approach to research in medicine and Quran. Results: In the verse of "Shifaa", the term “healing” is the opposite for the word loss and signifies richness, profit, and growth which eventually brings about calmness, evolvement, relief and safety. The foregoing results are achieved only by means of adherence to Quran and faithfulness which alternatively remedies all kind of diseases including loss, constraints, pressure, insecurity, restlessness and the like. Faith is the opposite of oppression and based on its lexical root means seeking refuge and safety under the shadow of Quran, and it is the only prerequisite for the Quranic therapy or healing. Oppression in Quranic concepts implies self-sufficiency and suffering, inattention to Quran, seeking help and security from else which consecutively is a path toward loss and damage. Conclusion: Reports of the research in Quran point out to the role and importance of the concept of faith in the Holy Quran and these reports provide reminders about the outcome of inattentiveness to the commands of the Holy Quran. To benefit from the Quranic therapy and Shiffa as mentioned in the Holy Quran, calls upon speculation and deep apprehension of the essence of the Quran along with its distinctive aspects.

Background and Objective: Chronic kidney disease (CKD) is a reticent but fatal disease worldwide. It is a health challenging issue due to its destructive, progressive and largely asymptomatic nature leading to kidney failure, accompanied by cardiovascular disease and costly treatment. Since there are fundamental problems increasing physician's effort in the process of diagnosis, electronic medical record system was designed in order to facilitate diagnosis by practitioners.

Materials and Methods: This research is of applied kind. The method of collecting information included books, articles, international system survey, patients' records and the use of questionnaires.

Results: The system was designed to provide instant access to patients’ records and detect stages of disease at the time of diagnosis and is deemed to be valuable due to its facility, speed and accuracy. Its primary stage use, support the accuracy of this software in eventual diagnosis by more than 5%.

Conclusion: Improved quality of care, accurate organization of medical records, ease of use and accessibility, decreased medical errors, immediate access to information in different places, decision -supporting technology and process improvement are among merits of this system.