Volume 19, Issue 76 (5-2011)                   J Adv Med Biomed Res 2011, 19(76): 77-83 | Back to browse issues page

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Eslami Raveshty S S, Eslami Raveshty S B. The Effect of Combining Essences of Myrtus Communis and Melissa Officinalis in the Treatment of Minor Aphta. J Adv Med Biomed Res 2011; 19 (76) :77-83
URL: http://journal.zums.ac.ir/article-1-1573-en.html
The Effect of Combining Essences of Myrtus Communis and Melissa Officinalis in the Treatment of Minor Aphta
Seyed Sina Eslami Raveshty *1 , Seyed Bahaodin Eslami Raveshty2
1- Abyek, Kimiadaru Pharmaceutical co. , Kimiadaru.pharmaceutical@yahoo.com
2- Abyek, Kimiadaru Pharmaceutical co.
Abstract:   (166063 Views)

Background and Objective: Minor aphta has a high incidence in the populations ranging from 2-50%. In spite of its frequency and severity of discomfort, there is not an absolute treatment for it. So, the main objective of this study was to evaluate the efficacy of a herbal medicine in the control of Minor aphta.   
Materials and Methods: In this double-blind, randomized study 137 patients with Minor aphta (with not more than four days from the onset) were selected and then placed into one of the groups of A (solution containing 5 percent Myrtus communis and Melissa officinalis in ethanol 80) and B (solution containing 10 percent Myrtus communis and Melissa officinalis in ethanol 80) or C (placebo containing ethanol 80).
Results: Mean duration for complete recovery in minor aphta was 3/5 days in group A, 7/5 days in group B and 7/3 days in group C. These results showed a significant statistical differences in the three groups
(p<0/0005).
Conclusion: The results of this study revealed that using a combination of Myrtus Communis and Melissa Officinalis plants was effective in the treatment of RAS. In order to obtain the accurate concentrations of the ingredients of this compound, further studies are necessary.

Keywords: Myrtus communis, Melissa officinalis, RAS (Recurrent Aphtous Stomatits), Mouth diseases
Full-Text [PDF 152 kb]   (160103 Downloads)    
Type of Study: Original Research Article |
Received: 2011/08/24 | Accepted: 2014/06/22 | Published: 2014/06/22
References
1. Ship JA, Levery k, Blomquist JE. Recurrent aphthous stomatitis An update. Oral Surg Oral med Oral Pathol Oral Radiol. 1996; 81: 141-7. [DOI:10.1016/S1079-2104(96)80403-3]
2. Bereket L, Rezaei M. Mouth disease of bereket diagnosis and treatment. Stomatitis aphthous: Tehran: Tehran university Publications; 19996.
3. Ship JA, Speigt PM, Morgan PR. Recurrent aphthous stomatitis. Quintessence Int. 2000; 31: 95-112.
4. Burgess JA, Johnson BD, Sommers E. Pharmacological management of recurrent oral mucosal ulceration. Drugs. 1990; 39: 54-65. [DOI:10.2165/00003495-199039010-00005] [PMID]
5. Rogers RS: Recurrent aphthous stomitis: clinical characteristic and evidence for an immunopathogenesis. J Investigative Dermatol. 1997; 69: 499-509. [DOI:10.1111/1523-1747.ep12687958] [PMID]
6. Mcbride DR, Macbride DR, Krause LS. Management of Aphthous ulcers. Am Family Physician. 2000; 62: 149-54.
7. Rodu B, Mattingly G. Oral Mucosal ulcers, Diagnosis and management. J AM Dent Assoc. 1992; 123: 83-6. [DOI:10.14219/jada.archive.1992.0268] [PMID]
8. Pyrovlia MJ. Evaluation of different products produced fron plant fruit perykarp Ulcery measures on oral mucosa, and ulcery pemfigus pest. [Dissertation]. Isfahan: Isfahan University of Medical Sciences; 1993.
9. Shariat S. Herbal extract material formed. Effective extraction and extraction methods herbs identify them. Isfahan: Isfahan Mani Publisher; 1992.
10. Brown RS, Bottomley WK. Combination immunosuppressant and Topical steroid therapy for treatment of recurrent major aphthous. Oral Surg Oral Med Oral Pathol. 1990; 69: 42-4. [DOI:10.1016/0030-4220(90)90266-U]
11. Katzung BG. Basic and clinical pharmacology. USA: Prentice- Hall International Inc; 1989.
12. Hedayati F. Clinical study of oral drugs and provide pest appropriate drug formulations. [Dissertation]. Isfahan: Isfahan University of Medical Sciences; 1992.
13. Hosseini azimi S, Mortazavi todashky A. Effect of Myrtus communis in mouth diseases therapy. Weekly Medical Science Today- especially herbs, 1999; 312: 1-3.
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