چهارشنبه 15 اسفند 1403
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دوره 25، شماره 113 - ( 6-1396 )
جلد 25 شماره 113 صفحات 102-91 |
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Mahmoudi Mourderaz Y, Chaman R, Malekhosseini S A A, Sharifi A, Khosravani S A, Taher Rezanejad M, et al . Antimicrobial Resistance Pattern and agr Typing among Staphylococcus aureus Isolated from Nasal Carrier Personnel in Shahid Beheshti Hospital in Yasuj City. J Adv Med Biomed Res 2017; 25 (113) :91-102
URL: http://journal.zums.ac.ir/article-1-4800-fa.html
URL: http://journal.zums.ac.ir/article-1-4800-fa.html
محمودی مورد راز یاسر، چمن رضا، ملک حسینی سید علی اصغر، شریفی اصغر، خسروانی سید عبدالمجید، طاهر رضا نژاد محمد، و همکاران.. تعیین الگوی مقاومت آنتی بیوتیکی و agr تایپینگ ایزوله‌های استافیلوکوکوس ارئوس جدا شده از ناقلین بینی در پرسنل بیمارستان شهید بهشتی شهر یاسوج. Journal of Advances in Medical and Biomedical Research. 1396; 25 (113) :91-102
یاسر محمودی مورد راز*1 
، رضا چمن1 ، سید علی اصغر ملک حسینی1 ، اصغر شریفی1 ، سید عبدالمجید خسروانی1 ، محمد طاهر رضا نژاد1 ، مریم حسنی1 ، رضا محمدی1 ، سید سجاد خرم روز1
، رضا چمن1 ، سید علی اصغر ملک حسینی1 ، اصغر شریفی1 ، سید عبدالمجید خسروانی1 ، محمد طاهر رضا نژاد1 ، مریم حسنی1 ، رضا محمدی1 ، سید سجاد خرم روز1
1- دانشگاه علوم پزشکی یاسوج
چکیده: (152738 مشاهده)
Background and Objective: Based on the important role of nasal carriers of Staphylococcus aureus in hospital settings and their importance in the transmission of bacterium to patients and other personnel, the aim of the present study was to determine the frequency of nasal carriers, antibiotic resistance patterns and genotyping of S. aureus isolated from personnel of Shahid Beheshti hospital in Yasuj city (Iran) using the agr typing method.
Materials and Methods: In this cross-sectional study, a total of 347 nasal samples were collected from the healthcare workers of Shahid Beheshti Hospital in order to identify S. aureus. Cefoxitin containing disks and detection of the mecA gene were used for the identification of methicillin resistant isolates. The antimicrobial susceptibility patterns of isolates were tested against 15 different antibiotics using the Disc Agar Diffusion method. The Multiplex-PCR method was used for the agr typing of S. aureus isolates.
Results: Ninety-three (26.8%) of personnel were nasal carriers of S. aureus, among them 9 isolates were identified as MRSA. Among agr groups, agrI (40.9%) and agrIII (40.9%) were the prominent genotypes. All of the isolates (100%) were resistant to Penicillin. The resistance rate to erythromycin and co-trimoxazole were 12.9% and 5.38% respectively. Most of the isolates were sensitive to other antibiotics.
Conclusion: Based on the low resistance rate of S. aureus, it appears that the eradication of nasal carrier states could be possible. S. aureus agr types I and III have an important role in nasal colonization in comparison to other agr types.
Materials and Methods: In this cross-sectional study, a total of 347 nasal samples were collected from the healthcare workers of Shahid Beheshti Hospital in order to identify S. aureus. Cefoxitin containing disks and detection of the mecA gene were used for the identification of methicillin resistant isolates. The antimicrobial susceptibility patterns of isolates were tested against 15 different antibiotics using the Disc Agar Diffusion method. The Multiplex-PCR method was used for the agr typing of S. aureus isolates.
Results: Ninety-three (26.8%) of personnel were nasal carriers of S. aureus, among them 9 isolates were identified as MRSA. Among agr groups, agrI (40.9%) and agrIII (40.9%) were the prominent genotypes. All of the isolates (100%) were resistant to Penicillin. The resistance rate to erythromycin and co-trimoxazole were 12.9% and 5.38% respectively. Most of the isolates were sensitive to other antibiotics.
Conclusion: Based on the low resistance rate of S. aureus, it appears that the eradication of nasal carrier states could be possible. S. aureus agr types I and III have an important role in nasal colonization in comparison to other agr types.
نوع مطالعه: کارآزمایی بالینی |
دریافت: 1396/6/5 | پذیرش: 1396/6/5 | انتشار: 1396/6/5
دریافت: 1396/6/5 | پذیرش: 1396/6/5 | انتشار: 1396/6/5
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