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Volume 8, Issue 30 (3-2000)
J Adv Med Biomed Res 2000, 8(30): 95-113 |
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Bigdeli M, Hjizadeh S. The Overveiw Of Pharmacologic Treatment Of Obstructive Sleep Apnea. J Adv Med Biomed Res 2000; 8 (30) :95-113
URL: http://journal.zums.ac.ir/article-1-497-en.html
URL: http://journal.zums.ac.ir/article-1-497-en.html
Abstract: (148033 Views)
The purpose of this study was reviewed by evidence based methodology about the use of pharmacologic agents for the treatment of sleep-disordered breathing. Evidence tables were created and studies were graded according to study design and the number of subjects induded. Each pharmacologic agent were established so that the quality of research for different drugs could be compared.The use of various ventilatory stimulants, psychotropic drugs, antihypertensive agents, and NO therapy. In controlled studies would be helpful, for use hypercapnic obesity - hypoventilation patients (Medroxy progestrone), myxedema (thyroid replacement), central apnea (aceta zolamide), periodic breathing in congestive heart failure (theophylline), and sikel cell (No therapy). Few randomized, well - controlled trials have been published that evaluate pharmacologic agents in the treatment of classic OSA. To date, no one agent stands out as being useful for OSA. Future research will need to characterize subjects so that various subsets of patients can be tried on one or on a combination of various pharmacologic agents.
Type of Study: Original Research Article |
Received: 2008/11/12 | Accepted: 2000/03/15 | Published: 2000/03/15
Received: 2008/11/12 | Accepted: 2000/03/15 | Published: 2000/03/15
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