Mon, Aug 24, 2026
[Archive]
Articles In Press
Back to the articles list |
Back to browse issues page
Navid Davoodi1 
, Nahid Kianmehr2 , Anousheh Haghighi3 , Azadeh Goodarzi4 , Amirhosein Gholamlou *5 , Ali Sepyani3
, Nahid Kianmehr2 , Anousheh Haghighi3 , Azadeh Goodarzi4 , Amirhosein Gholamlou *5 , Ali Sepyani3
1- Department of Internal Medicine, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
2- Department of Internal Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
3- Department of Rheumatology, Rasoul Akram Hospital, Tehran, Iran
4- Department of Dermatology, Rasoul Akram Medical Complex Clinical Research Development Center (RCRDC), Tehran, Iran & Department of Dermatology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
5- Department of Internal Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran & Department of Internal Medicine, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran ,amirgholamlou@gmail.com
2- Department of Internal Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
3- Department of Rheumatology, Rasoul Akram Hospital, Tehran, Iran
4- Department of Dermatology, Rasoul Akram Medical Complex Clinical Research Development Center (RCRDC), Tehran, Iran & Department of Dermatology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
5- Department of Internal Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran & Department of Internal Medicine, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran ,
Abstract: (272 Views)
Background and Objectives: Early detection of joint involvement, often as enthesitis, is vital in psoriasis to prevent permanent damage. This study aimed to assess patellar tendon changes via ultrasonography in psoriasis patients and compare them with healthy controls.
Materials and Methods: In this case-control study, 30 patients with cutaneous psoriasis as the case group and 30 healthy controls who fulfilled both the inclusion and exclusion criteria were included. Ultrasound examination of the thickness of the patellar tendon was performed in the distal and proximal areas of both knees. Statistical analysis was performed using SPSS v26 software with a significance level of 0.05.
Results: There was no significant difference in the average thickness of the proximal patellar tendon in the dominant knee (p=0.911) and the non-dominant knee (p=0.337) in comparing the psoriasis group and the healthy control. Also, there was no statistically significant difference between the two groups in the measurement of the distal area of the tendon in the dominant limb (p=0.154) and non-dominant limb (p=0.073).
Conclusion: It was found that the thickness of the proximal and distal patellar tendon in the dominant limb as well as the non-dominant limb in people with cutaneous psoriasis is not different from healthy people.
Materials and Methods: In this case-control study, 30 patients with cutaneous psoriasis as the case group and 30 healthy controls who fulfilled both the inclusion and exclusion criteria were included. Ultrasound examination of the thickness of the patellar tendon was performed in the distal and proximal areas of both knees. Statistical analysis was performed using SPSS v26 software with a significance level of 0.05.
Results: There was no significant difference in the average thickness of the proximal patellar tendon in the dominant knee (p=0.911) and the non-dominant knee (p=0.337) in comparing the psoriasis group and the healthy control. Also, there was no statistically significant difference between the two groups in the measurement of the distal area of the tendon in the dominant limb (p=0.154) and non-dominant limb (p=0.073).
Conclusion: It was found that the thickness of the proximal and distal patellar tendon in the dominant limb as well as the non-dominant limb in people with cutaneous psoriasis is not different from healthy people.
Type of Study: Original Research Article |
Subject:
Clinical Medicine
Received: 2025/03/9 | Accepted: 2026/06/22
Received: 2025/03/9 | Accepted: 2026/06/22
References
1. Michalek IM, Loring B, John SM. A systematic review of worldwide epidemiology of psoriasis. J Eur Acad Dermatol Venereol. 2017; 31(2): 205-12. [DOI:10.1111/jdv.13854] [PMID] [PMCID]
2. Kulkarni V, Liu D, Gamsarian V, Grewal T, Sivesind T. Risk factors associated with burden of disease of psoriasis from 1990 to 2019: epidemiological analysis. JMIR Dermatol. 2024; 7: e48749. [DOI:10.2196/48749] [PMID] [PMCID]
3. Alizadeh N, Darjani A, Porabbas m. Epidemiology and clinical features of psoriasis patients admitted to a dermatology ward. J Guilan Univ Med Sci. 2019; 28(110 #ng0061): 1-7.
4. Brauchli YB, Jick SS, Miret M, Meier CR. Psoriasis and risk of incident myocardial infarction, stroke or transient ischaemic attack: an inception cohort study with a nested case-control analysis. Br J Dermatol. 2009; 160(5): 1048-56. [DOI:10.1111/j.1365-2133.2008.09020.x] [PMID]
5. Chen YJ, Chang YT, Shen JL, Chen TT, Wang CB, Chen CM, et al. Association between systemic antipsoriatic drugs and cardiovascular risk in patients with psoriasis with or without psoriatic arthritis: a nationwide cohort study. Arthritis Rheum. 2012; 64(6): 1879-87. [DOI:10.1002/art.34335] [PMID]
6. Schett G, Rahman P, Ritchlin C, McInnes IB, Elewaut D, Scher JU. Psoriatic arthritis from a mechanistic perspective. Nat Rev Rheumatol. 2022; 18(6): 311-25. [DOI:10.1038/s41584-022-00776-6] [PMID]
7. Gisondi P, Tinazzi I, El-Dalati G, Gallo M, Biasi D, Barbara LM, et al. Lower limb enthesopathy in patients with psoriasis without clinical signs of arthropathy: a hospital-based case-control study. Ann Rheum Dis. 2008; 67(1): 26-30. [DOI:10.1136/ard.2007.075101] [PMID]
8. Simon D, Tascilar K, Kleyer A, Bayat S, Kampylafka E, Sokolova M, et al. Structural entheseal lesions in patients with psoriasis are associated with an increased risk of progression to psoriatic arthritis. Arthritis Rheumatol. 2022;74(2):253-62 [DOI:10.1002/art.41239] [PMID]
9. Vyas K, Jain SK, Mittal A, Kumar R, Saxena S, Malviya S. Sonographic evaluation of subclinical enthesopathy in patients of chronic plaque psoriasis. Indian Dermatol Online J. 2020; 11(4): 580-5. [DOI:10.4103/idoj.IDOJ_446_18] [PMID] [PMCID]
10. Graceffa D, Bonifati C, Lora V, Saraceni PL, De Felice C, Chimenti MS, et al. Ultrasound assessment of enthesis thickness in psoriasis and psoriatic arthritis: A cross-sectional study. Indian J Dermatol Venereol Leprol. 2019; 85: 175. [DOI:10.4103/ijdvl.IJDVL_205_17] [PMID]
11. McGonagle D, Marzo-Ortega H, O'connor P, Gibbon W, Hawkey P, Henshaw K, et al. Histological assessment of the early enthesitis lesion in spondyloarthropathy. Ann Rheum Dis. 2002; 61(6): 534-7. [DOI:10.1136/ard.61.6.534] [PMID] [PMCID]
12. Hussein SA, Elhefny AM, Abdulrahman MA, Aziz NN. Early detection of subclinical lower limb enthesopathy by ultrasonography in patients with psoriasis: Relation to disease severity. Egypt Rheumatol. 2021; 43(2): 153-7. [DOI:10.1016/j.ejr.2021.01.004]
13. Macía‐Villa C, Cruz Valenciano A, De Miguel E. Enthesis lesions are associated with X‐ray progression in psoriatic arthritis. Int J Rheum Dis. 2021; 24(6): 828-33. [DOI:10.1111/1756-185X.14122] [PMID]
14. Smerilli G, Cipolletta E, Castaniti GMD, Di Matteo A, Di Carlo M, Moscioni E, et al. Doppler signal and bone erosions at the enthesis are independently associated with ultrasound joint erosive damage in psoriatic arthritis. J Rheumatol. 2023; 50(1): 70-5. [DOI:10.3899/jrheum.210974] [PMID]
15. van der Ven M, Karreman MC, Weel AE, Tchetverikov I, Vis M, Nijsten TE, et al. Adding ultrasound to clinical examination reduced frequency of enthesitis in primary care psoriasis patients with musculoskeletal complaints. Clin Exp Rheumatol. 2016; 34(6): 1020-5.
16. Tang Y, Yang Y, Xiang X, Wang L, Zhang L, Qiu L. Power doppler ultrasound evaluation of peripheral joint, entheses, tendon, and bursa abnormalities in psoriatic patients: A clinical study. J Rheumatol. 2018; 45(6): 811-7. [DOI:10.3899/jrheum.170765] [PMID]
17. Macchioni P, Salvarani C, Possemato N, Gutierrez M, Grassi W, Gasparini S, et al. Ultrasonographic and clinical assessment of peripheral enthesitis in patients with psoriatic arthritis, psoriasis, and fibromyalgia syndrome: The ULISSE Study. J Rheumatol. 2019; 46(8): 904-11. [DOI:10.3899/jrheum.171411] [PMID]
18. D'Agostino MA, Aegerter P, Bechara K, Salliot C, Judet O, Chimenti MS, et al. How to diagnose spondyloarthritis early? Accuracy of peripheral enthesitis detection by power Doppler ultrasonography. Ann Rheum Dis. 2011; 70(8): 1433-40. [DOI:10.1136/ard.2010.138701] [PMID]
19. Eder L, Jayakar J, Thavaneswaran A, Haddad A, Chandran V, Salonen D, et al. Is the MAdrid sonographic enthesitis index useful for differentiating psoriatic arthritis from psoriasis alone and healthy controls? J Rheumatol. 2014; 41(3): 466-72. [DOI:10.3899/jrheum.130949] [PMID]
20. Lewinson RT, Vallerand IA, Parsons LM, LaMothe JM, Frolkis AD, Lowerison MW, et al. Psoriasis and the risk of foot and ankle tendinopathy or enthesopathy in the absence of psoriatic arthritis: a population-based study. RMD open. 2018; 4(1): e000668. [DOI:10.1136/rmdopen-2018-000668] [PMID] [PMCID]
21. Erdem CZ, Tekin NS, Sarikaya S, Erdem LO, Gulec S. MR imaging features of foot involvement in patients with psoriasis. Eur J Radiol. 2008; 67(3): 521-5. [DOI:10.1016/j.ejrad.2007.08.005] [PMID]
22. Gisondi P, Tinazzi I, El-Dalati G, Gallo M, Biasi D, Barbara LM, et al. Lower limb enthesopathy in patients with psoriasis without clinical signs of arthropathy: a hospital-based case-control study. Ann Rheum Dis. 2008; 67(1): 26-30. [DOI:10.1136/ard.2007.075101] [PMID]
23. Karamanlioglu DS, Ozkan FU, Arikan E, Pirdal BZ, Ozturk G, Aktas I. Detection of subclinical enthesitis by ultrasonography in patients with psoriasis and controls. ARP Rheumatol. 2024; 3(1). [DOI:10.63032/UNBM9076] [PMID]
24. Dascălu RC, Bărbulescu AL, Dinescu ȘC, Biță CE, Stoica LE, Vreju FA. Subclinical enthesopathy in psoriasis-An ultrasonographic study. Med Sci. 2024; 12(3): 40. [DOI:10.3390/medsci12030040] [PMID] [PMCID]
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Copyright Policy
Journal of Advances in Medical and Biomedical Research by Zanjan University of Medical Sciences is licensed under CC BY-NC 4.0
