دوره 19، شماره 75 - ( 2-1390 )                   جلد 19 شماره 75 صفحات 83-77 | برگشت به فهرست نسخه ها

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Nabavi S, Behzad Moghadam M H, Arab Hosseini M H, Vaezi M, Rajabi R. Evaluation of Auditory Brainstem Responses (ABR) in Healthy Term Infants with Elevated Bilirubin Levels Requiring Exchange Transfusion. J Adv Med Biomed Res 2011; 19 (75) :77-83
URL: http://journal.zums.ac.ir/article-1-1494-fa.html
نبوی سعید، بهزادمقدم محمدحسین، عرب حسینی محمدحسین، واعظی مهناز، رجبی رضا. بررسی شنوایی‌سنجی (ABR) نوزادان ترم سالم بستری با بیلی‌روبین بالای در حد تعویض خون. Journal of Advances in Medical and Biomedical Research. 1390; 19 (75) :77-83

URL: http://journal.zums.ac.ir/article-1-1494-fa.html


1- متخصص اطفال، استادیار دانشکده پزشکی دانشگاه آزاد اسلامی واحد تهران ، nabavi.saeed@gmail.com
2- فوق تخصص نوزادان، دانشیار دانشگاه علوم پزشکی تهران
3- کارشناس بهداشت محیط، دانشگاه آزاد اسلامی واحد تهران
4- کارشناس شنوایی سنجی، دانشگاه علوم پزشکی تهران
چکیده:   (173097 مشاهده)

Background and Objective: Hyperbilirubinemia is a common neonatal abnormality. Severe hyperbilirubinemia is a risk factor for auditory system injury. Auditory brainstem responses (ABR) are important in early diagnosis of hearing impairments in healthy term infants with elevated bilirubin levels requiring exchange transfusion.
Materials and Methods: During a two- year- period (2007 – 2009), in a prospective descriptive analytical study, in Tehran Milad Hospital, 64 (32 female, 32 male), healthy term (> 37 weeks) infants, who required treatment or were treated with phototherapy or received exchange transfusion for elevated bilirubin levels or jaundice, were studied. After obtaining a written consent from their parents, the infants were tested with auditory brain responses and results were analyzed using SPSS 16 software.
Results: No significant correlation was found between ABR and age, weight, bilirubin level or ABO blood group. Nineteen out of 64 infants received exchange transfusion. Three out of 19 infants (16%) exhibited abnormal ABR and 16 infants (84%) had normal ABR. There was no significant correlation between exchange transfusions and ABR (P>0.05).  
Conclusion: The results pointed out that 14% of the infants with elevated bilirubin who required exchange transfusion had abnormal ABR. This indicates that elevated bilirubin levels even without inducing kernicterus should be considered as risk factors for hearing impairments. Further studies are needed on how long these tests may remain abnormal.

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نوع مطالعه: مقاله پژوهشی |
دریافت: 1390/3/18 | پذیرش: 1393/4/1 | انتشار: 1393/4/1

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