Shingles is a delayed reactivation of varicella zoster virus as an outcome of sensory ganglia. Manifestation of sensory symptoms and vesicular dermatomal rashes in sensory area of involved nerve root is an expected event in the activation of herpes from sensory afferents whereby motor weakness and paralysis rarely occur. The present case was a 64-year old man with diabetes and immunodeficiency caused by immune-suppressant drugs. After appearance of vesicular rashes in the right leg, he had difficulty in walking due to motor weakness of the right leg.