Background and Objectives: Obesity is a major risk factor of cardiovascular diseases. Visceral adipose tissue (VAT) plays an important role in complications obesity. Although the measurement of waist circumference is a useful index for evaluating obesity and its complications, always increasing of waist circumference is not associated with VAT accumulation. HTGW (Hypertriglyceridemic waist circumference) phenotype is a useful marker for visceral adipose tissue accumulation. The purpose of this study is comparison of sdLDL-c serum level and LDL-c particle size as risk factors for cardiovascular diseases in middle aged woman with HTGW phenotype and without it. Materials and Methods: For this purpose, 90 volunteer women between 40 and 60 years old based on the four common definitions of HTGW phenotype, were divided into two groups with and without this phenotype. It was used precipitation method for measurement of serum levels of sdLDL-c. 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