دوره 10، شماره 41 - ( 10-1381 )                   جلد 10 شماره 41 صفحات 23-15 | برگشت به فهرست نسخه ها

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Moghaddamnia A, Bisheh Sari N. Protective Effect Of Alcohol On Muscle Paralysis Induced By Atracorium. J Adv Med Biomed Res 2002; 10 (41) :15-23
URL: http://journal.zums.ac.ir/article-1-334-fa.html
مقدم نیا علی اکبر، بیشه سری نیما. اثر حفاظتی‌ اتانل‌ بر فلج‌ عضلانی‌ ناشی‌ از آتراکوریوم‌ در عضله‌ ‌دو بطنی‌ گردنی‌ جوجه‌. Journal of Advances in Medical and Biomedical Research. 1381; 10 (41) :15-23

URL: http://journal.zums.ac.ir/article-1-334-fa.html


چکیده:   (150469 مشاهده)
Introduction: Regarding the side effects of muscle relaxants especially non - depolarizing agents, this study was done to determine the protective effect of alcohol on muscle paralysis induced by atracurium in preparation of isolated chicken biventer cervices muscle.
Materials and Methods: This experimental study was performed on two groups of chicken biventer cervices muscles. In each group, 6 chickens were recruited. After inserting the muscles in an organ bath containing Tirod physiologic solution and oxygen at 37°c, atracurium was introduced to the first group. A combination of alcohol and atracurium was added to the second group. The percentage of muscle paralysis and duration of contraction in each group were then registered. A student t-test was performed for analysis of the data.
Results: Percent of muscle paralysis followed by atracurium introduction in chick biventer cervices muscle was decreased in the presence of ethanol (p<0.01). Duration of paralysis was decreased also in the group receiving ethanol compared with the group receiving atracurium alone (p<0.01).
Conclusion: Results suggested that ethanol with possible presynaptic and postsynaptic effects can protect the muscle against the paralysis induced by atracurium.
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نوع مطالعه: مقاله پژوهشی |
دریافت: 1387/7/7 | پذیرش: 1396/3/28 | انتشار: 1396/3/28

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