دوره ۲۴، شماره ۱۰۴ - ( ۳-۱۳۹۵ )                   جلد ۲۴ شماره ۱۰۴ صفحات ۱۰۱-۹۴ | برگشت به فهرست نسخه ها

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Jafari M, Bahaoddini A, Khoshnam S E, Owjfard M. The Effect of Prolonged Exposure to Extremely Low-Frequency Electromagnetic Fields on the Nitrergic System in Small Intestine of Male Rats. J Adv Med Biomed Res 2016; 24 (104) :94-101
URL: http://journal.zums.ac.ir/article-1-3536-fa.html
جعفری مرضیه، بهاالدینی امین‌الله، خوشنام سید اسماعیل، اوج فرد مریم. بررسی اثر قرارگیری طولانی مدت در معرض امواج الکترومغناطیس با فرکانس فوق‌العاده پایین بر فعالیت سیستم نیتررژیک در روده‌ی باریک موش صحرایی نر. Journal of Advances in Medical and Biomedical Research. ۱۳۹۵; ۲۴ (۱۰۴) :۹۴-۱۰۱

URL: http://journal.zums.ac.ir/article-۱-۳۵۳۶-fa.html


۱- دانشگاه شیراز
۲- دانشگاه علوم پزشکی جندی شاپور اهواز ، esmaeil.khoshnam1392@gmail.com
۳- دانشگاه علوم پزشکی جندی شاپور اهواز
چکیده:   (۱۵۰۷۷۹ مشاهده)

Background and Objective: Nitric Oxide in the small intestine causes relaxation of smooth muscles. Research indicates that extremely low frequency electromagnetic fields (ELF) affect nitric oxide level in the tissues. The objective of this study was to grasp the effect of prolonged exposure to ELF on the nitrergic system in the small intestine.

Materials and Methods: 21 adult male rats were allocated to three groups: the experimental group exposed to ELF (50Hz, 1mT) for 75 days, the sham-operated group underwent similar conditions except ELF exposure; and the control group mice were kept under the laboratory normal condition. The isolated strips of the colon were inserted into organ bath and were linked to force transducer power lab A to D system and their mechanical activity were recorded in response to L-NAME. Data was analyzed using one way ANOVA test.

Results: The results exhibited a significant increase (p≤0.05) of ileum basal contractions in experimental group when compared to control and sham groups. However, administration of L-NAME (inhibitor of NO synthesis) led to a significant decrease in ileum contraction in the experimental group compared to the sham and control groups (p≤0.05).

Conclusion: It can be concluded that prolonged exposure to extremely low-frequency electromagnetic fields may decrease the activity of nitrergic system in small intestine of the male rats.

متن کامل [PDF 227 kb]   (۱۵۷۷۲۰ دریافت)    
نوع مطالعه: کارآزمایی بالینی |
دریافت: 1394/11/24 | پذیرش: 1394/11/24 | انتشار: 1394/11/24

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