Background: Considering the role of iodine deficiency in gaiter formation and its effect on the function of thyroid, and also since our previous study in 1993 showed a severe iodine deficiency in Ahar (a rural area in north of Tehran), this study was carried out after 6 years to monitor the iodine supplementation program in schoolchildren aged 6-14 years.
Materials and Methods: This descriptive study was conducted on 61 female schoolchldren who had received iodized oil injection. Then, goiter grade was measured by palation based on WHO classification. Thyroid hormones concentration was measured by commercial kits and urinary iodine by digestion method. The results were compared with the data obtained from our previous research in 1993.
Results: A significant decrease in grade 2 goiter from 86% in 1993 to 5% in 1999 (P<0.001) and also a great increase in grade 1 goiter from 10% to 53% (P<0.001) were observed. Gaiter prevalence decreased 39%. The Mean level of urinary iodine excretion showed a remarkable increase from 1993 to 1999 (P<0.001).Serums T4, T3, TSH, and RT3UP were in normal ranges. The mean hormones levels in 1993 and 1999 were 160±41 and 151.626 ng/di for T3, 4.7±1.9 and 1.3±0.7 g/ml (P<0.001) for TSH and 30±4 and 28±25% for RT3UP respectively.
نوع مطالعه:
مقاله پژوهشی |
دریافت: 1387/8/20 | پذیرش: 1381/3/25 | انتشار: 1381/3/25