جمعه 26 اردیبهشت 1404
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دوره 10، شماره 38 - ( 1-1381 )
جلد 10 شماره 38 صفحات 21-17 |
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Jalili Nadushan M, Hashemi M, Valaei N. Role Of Abo Blood Groups As Prognostic Factors In Primary Breast Cancer. J Adv Med Biomed Res 2002; 10 (38) :17-21
URL: http://journal.zums.ac.ir/article-1-417-fa.html
URL: http://journal.zums.ac.ir/article-1-417-fa.html
جلالی ندوشن محمد رضا، هاشمی مجتبی، ولایی ناصر. ارتباط گروههای خونی ABO با پیش آگهی سرطان اولیه پستان. Journal of Advances in Medical and Biomedical Research. 1381; 10 (38) :17-21
چکیده: (148445 مشاهده)
Background: Breast cancer is one of the most common malignancies of females. Multiple prognostic factors have been determined for this cancer. In order to determine the relationship between ABO blood groups and prognosis of primary breast cancer, this study was conducted in three teaching-hospitals in Tehran from 1994 until 2000.
Materials and methods: This study was carried out on 200 patients with breast cancer in a case-control method. Tumor size less than 2.5cm without lymph node involvement was classified as good prognosis in 100 subjects and tumor size greater than 2.5cm with lymph node metastasis was classified as poor prognosis in 100 patients. 1000 healthily subjects were selected as the second control group. Then, the data were analyzed statistically and odds ratio and confidence interval were estimated.
Results: Blood group distribution in normal population and patients with breast cancer does not have any statistical difference. Patients with AB and B blood groups had increased the chance for poor prognosis of breast cancer. The prevalence of B and AB blood groups in patients with poor prognosis breast cancer was higher than those with good prognosis cancer (45% VS. 31%, and O.R: 1.8).
Conclusion: There is a relationship between the antigen of blood group B and bad prognosis of breast cancer. To confirm this claim, some prospective studies are recommended.
Materials and methods: This study was carried out on 200 patients with breast cancer in a case-control method. Tumor size less than 2.5cm without lymph node involvement was classified as good prognosis in 100 subjects and tumor size greater than 2.5cm with lymph node metastasis was classified as poor prognosis in 100 patients. 1000 healthily subjects were selected as the second control group. Then, the data were analyzed statistically and odds ratio and confidence interval were estimated.
Results: Blood group distribution in normal population and patients with breast cancer does not have any statistical difference. Patients with AB and B blood groups had increased the chance for poor prognosis of breast cancer. The prevalence of B and AB blood groups in patients with poor prognosis breast cancer was higher than those with good prognosis cancer (45% VS. 31%, and O.R: 1.8).
Conclusion: There is a relationship between the antigen of blood group B and bad prognosis of breast cancer. To confirm this claim, some prospective studies are recommended.
نوع مطالعه: مقاله پژوهشی |
دریافت: 1387/8/20 | پذیرش: 1380/12/24 | انتشار: 1380/12/24
دریافت: 1387/8/20 | پذیرش: 1380/12/24 | انتشار: 1380/12/24
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